Analysis of crystal size dispersion effects in a continuous coiled tubular crystallizer: experiments and modeling

L Hohmann, T Greinert, O Mierka, S Turek… - Crystal Growth & …, 2018 - ACS Publications
Continuous processing gains importance in the fine chemical and pharmaceutical industries
where crystallization is an important downstream operation. Seeded cooling crystallization …

Crystal shape modification via cycles of growth and dissolution in a tubular crystallizer

P Neugebauer, J Cardona, MO Besenhard… - Crystal growth & …, 2018 - ACS Publications
Besides size and polymorphic form, crystal shape takes a central role in engineering
advanced solid materials for the pharmaceutical and chemical industries. This work …

Systematic model identification and optimization-based active polymorphic control of crystallization processes

E Simone, B Szilagyi, ZK Nagy - Chemical Engineering Science, 2017 - Elsevier
Polymorphism is an important issue in industrial crystallization, since polymorphs of the
same compound can present very different properties, such as solubility, melting point or …

Parameter Estimation in Population Balance through Bayesian‎ Technique Markov Chain Monte Carlo

CHR Moura, BM Viegas, MRM Tavares… - Journal of Applied and …, 2021 - jacm.scu.ac.ir
In this work, the Markov Chain Monte Carlo is applied to estimate parameters that represent
mechanisms that describe particles' dynamics in particulate systems from the literature's …

Multi-dimensional population balance modeling of sonocrystallization of pyrazinamide with systematic estimation of kinetic parameters based on uncertainty and …

A Maharana, P Sehrawat, A Das, J Kumar… - … Research and Design, 2023 - Elsevier
Application of ultrasound has several beneficial effects on both crystallization process and
product crystal properties. This work focuses on experimental study and population balance …

Crystallization of Calcium Carbonate: Modeling Thermodynamic Equilibrium, Pathway, Nucleation, Growth, Agglomeration, and Dissolution Kinetics with the Presence …

T Machado Neubauer, F Santos Serpa… - Industrial & …, 2022 - ACS Publications
Calcium carbonate (CaCO3) crystallization is a complex operation due to the diverse
thermodynamic and kinetic factors involved during the particle formation of vaterite …

Statistical Analyses of a Population Balance Model of a Batch Crystallization Process

FARD Lima, G Barreto Correa… - Crystal Growth & …, 2023 - ACS Publications
Crystallization is a widely employed separation technique that has received significant
attention due to its industrial relevance, notably in the pharmaceutical industry. While …

Kinetic study of complicated anti-solvent and cooling crystallization of disodium 5′-ribonucleotide

W Zhao, B Li, S Liu, Y Deng, R Zhang, Y Jiang - Particuology, 2023 - Elsevier
Abstract Disodium 5′-ribonucleotide, which is composed of disodium 5′-inosine (IMP)
and disodium 5′-guanosine (GMP), is an important food additive. The lack of kinetic studies …

Coupled population balance and species balance models of crystallization: Analytic solutions and data fits

V Bal, B Peters - Crystal Growth & Design, 2020 - ACS Publications
Obtaining kinetic constants in rate laws for nucleation and growth is challenging and
essential to the design of the crystallization processes. Starting from the coupled species …

Crystallization process analysis by population balance modeling

ÅC Rasmuson - Handbook of Industrial Crystallization, 2019 - cambridge.org
In the area of industrial crystallization, population balances are used to model how the
number and properties of the crystals in a crystallizer are generated and eventually appear …