International consensus statement on allergy and rhinology: rhinosinusitis 2021
RR Orlandi, TT Kingdom, TL Smith… - International forum of …, 2021 - Wiley Online Library
I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …
Formation, signaling and occurrence of specialized pro-resolving lipid mediators—what is the evidence so far?
Formation of specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins
usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of …
usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of …
Mechanisms of dupilumab
H Harb, TA Chatila - Clinical & Experimental Allergy, 2020 - Wiley Online Library
The Th2 cytokines interleukin 4 (IL‐4) and IL‐13 and the heterodimeric IL‐4 receptor (IL‐4R)
complexes that they interact with play a key role in the pathogenesis of allergic disorders …
complexes that they interact with play a key role in the pathogenesis of allergic disorders …
Endotypes of chronic rhinosinusitis: relationships to disease phenotypes, pathogenesis, clinical findings, and treatment approaches
Chronic rhinosinusitis (CRS) is a common clinical syndrome that produces significant
morbidity and costs to our health system. The study of CRS has progressed from an era …
morbidity and costs to our health system. The study of CRS has progressed from an era …
Advances and highlights in biomarkers of allergic diseases
During the past years, there has been a global outbreak of allergic diseases, presenting a
considerable medical and socioeconomical burden. A large fraction of allergic diseases is …
considerable medical and socioeconomical burden. A large fraction of allergic diseases is …
Epidemiology of chronic rhinosinusitis: prevalence and risk factors
AR Sedaghat, EC Kuan, GK Scadding - The Journal of Allergy and Clinical …, 2022 - Elsevier
Knowledge of chronic rhinosinusitis (CRS) epidemiology may directly impact patient care:
aiding patient identification and establishing accurate diagnosis as well as informing …
aiding patient identification and establishing accurate diagnosis as well as informing …
Single-cell profiling identifies mechanisms of inflammatory heterogeneity in chronic rhinosinusitis
W Wang, Y Xu, L Wang, Z Zhu, S Aodeng, H Chen… - Nature …, 2022 - nature.com
The heterogeneous cellular microenvironment of human airway chronic inflammatory
diseases, including chronic rhinosinusitis (CRS) and asthma, is still poorly understood …
diseases, including chronic rhinosinusitis (CRS) and asthma, is still poorly understood …
Severe adult asthmas: integrating clinical features, biology, and therapeutics to improve outcomes
SE Wenzel - American journal of respiratory and critical care …, 2021 - atsjournals.org
Evaluation and effective management of asthma, and in particular severe asthma, remains
at the core of pulmonary practice. Over the last 20–30 years, there has been increasing …
at the core of pulmonary practice. Over the last 20–30 years, there has been increasing …
Eosinophilic chronic rhinosinusitis
S Fujieda, Y Imoto, Y Kato, T Ninomiya… - Allergology …, 2019 - jstage.jst.go.jp
abstract Eosinophilic chronic rhinosinusitis (ECRS) is a subgroup of chronic rhinosinusitis
with nasal polyps (CRSwNP), which is associated with severe eosinophilic infiltration and …
with nasal polyps (CRSwNP), which is associated with severe eosinophilic infiltration and …
Adult‐onset eosinophilic airway diseases
K Asano, S Ueki, M Tamari, Y Imoto, S Fujieda… - Allergy, 2020 - Wiley Online Library
Eosinophilic airway inflammation is one of the cardinal features of allergic airway diseases
such as atopic asthma and allergic rhinitis. These childhood‐onset conditions are mediated …
such as atopic asthma and allergic rhinitis. These childhood‐onset conditions are mediated …