The metabolite 2-oxoglutarate (also known as α-ketoglutarate, 2-ketoglutaric acid, or
oxoglutaric acid) lies at the intersection between the carbon and nitrogen metabolic …

Metabolically versatile free-living bacteria have global regulation systems that allow cells to
selectively assimilate a preferred compound among a mixture of several potential carbon …

Summary mRNAs can fold into complex structures that regulate gene expression. Resolving
such structures de novo has remained challenging and has limited our understanding of the …

Analysis of the 1,042,519–base pair Chlamydia trachomatis genome revealed unexpected
features related to the complex biology of chlamydiae. Although chlamydiae lack many …

The complete genome sequence of Treponema pallidum was determined and shown to be
1,138,006 base pairs containing 1041 predicted coding sequences (open reading frames) …

▪ Abstract Nitrogen limitation in Escherichia coli controls the expression of about 100 genes
of the nitrogen regulated (Ntr) response, including the ammonia-assimilating glutamine …

Carbon catabolite repression (CCR) is a regulatory mechanism by which the expression of
genes required for the utilization of secondary sources of carbon is prevented by the …

We present a comprehensive overview of the hierarchical network of intracellular processes
revolving around central nitrogen metabolism in Escherichia coli. The hierarchy intertwines …

The initiation of transcription is the most important step for gene regulation in eubacteria. To
initiate transcription, RNA polymerase has to associate with a small protein, known as a σ …

An overview was made to understand the regulation system of a bacterial cell such as
Escherichia coli in response to nutrient limitation such as carbon, nitrogen, phosphate …