Role of interferons in the antiviral battle: from virus-host crosstalk to prophylactic and therapeutic potential in SARS-CoV-2 infection
Mammalians sense antigenic messages from infectious agents that penetrate the respiratory
and digestive epithelium, as well as signals from damaged host cells through membrane …
and digestive epithelium, as well as signals from damaged host cells through membrane …
ACE2 and TMPRSS2 genetic polymorphisms as potential predictors of COVID−19 severity and outcome in females
S Matic, D Milovanovic, Z Mijailovic, P Djurdjevic… - Frontiers in …, 2024 - frontiersin.org
Introduction ACE2 and TMPRSS2 represent the major gateways for SARS-CoV-2 cell entry.
The presence of functional ACE2 and TMPRSS2 genetic polymorphisms that affect gene …
The presence of functional ACE2 and TMPRSS2 genetic polymorphisms that affect gene …
Evidence for a sex-dependent effect modification in the association between IFN-λ DNA polymorphisms and expression of IFN-λ and interferon-stimulated genes in …
DG Roy, M De, S Bharatiya, DA Khedekar, K Datta… - Cytokine, 2024 - Elsevier
Human interferon (IFN) lambda (IFNL, IFN-L or IFN-λ) locus has several functional genetic
variants but their role in regulating in vivo gene expression, and whether they associate with …
variants but their role in regulating in vivo gene expression, and whether they associate with …
FURIN, IFNL4, and TLR2 gene polymorphisms in relation to COVID-19 severity: a case–control study in Egyptian patients
Methods 150 adult COVID-19-assured cases were categorized as follows: 78 patients with a
non-severe presentation, 39 patients with severe disease, and 33 critically ill patients. In …
non-severe presentation, 39 patients with severe disease, and 33 critically ill patients. In …