Development, wiring and function of dopamine neuron subtypes

O Garritsen, EY van Battum, LM Grossouw… - Nature Reviews …, 2023 - nature.com
The midbrain dopamine (mDA) system is composed of molecularly and functionally distinct
neuron subtypes that mediate specific behaviours and are linked to various brain diseases …

[HTML][HTML] Midbrain dopaminergic neurons: a review of the molecular circuitry that regulates their development

SV Hegarty, AM Sullivan, GW O'keeffe - Developmental biology, 2013 - Elsevier
Dopaminergic (DA) neurons of the ventral midbrain (VM) play vital roles in the regulation of
voluntary movement, emotion and reward. They are divided into the A8, A9 and A10 …

Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis

J Wu, J Bao, M Kim, S Yuan, C Tang… - Proceedings of the …, 2014 - National Acad Sciences
Ablation of a single miRNA gene rarely leads to a discernable developmental phenotype in
mice, in some cases because of compensatory effects by other functionally related miRNAs …

Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors

CH Yan, M Levesque, S Claxton… - Journal of …, 2011 - Soc Neuroscience
LIM homeodomain transcription factors, Lmx1a and Lmx1b, are required for the
development of midbrain dopaminergic (mDA) neurons. Lmx1b is required for the …

The discovery of the growth cone and its influence on the study of axon guidance

E Tamariz, A Varela-Echavarría - Frontiers in neuroanatomy, 2015 - frontiersin.org
For over a century, there has been a great deal of interest in understanding how neural
connectivity is established during development and regeneration. Interest in the latter arises …

Globularity and language-readiness: generating new predictions by expanding the set of genes of interest

C Boeckx, A Benítez-Burraco - Frontiers in Psychology, 2014 - frontiersin.org
This study builds on the hypothesis put forth in, according to which the developmental
changes expressed at the levels of brain morphology and neural connectivity that resulted in …

Neuronal subset-specific migration and axonal wiring mechanisms in the developing midbrain dopamine system

S Brignani, RJ Pasterkamp - Frontiers in Neuroanatomy, 2017 - frontiersin.org
The midbrain dopamine (mDA) system is involved in the control of cognitive and motor
behaviors, and is associated with several psychiatric and neurodegenerative diseases. mDA …

Role of netrin-1 in the organization and function of the mesocorticolimbic dopamine system

C Flores - Journal of Psychiatry and Neuroscience, 2011 - jpn.ca
Changes in mesocorticolimbic dopamine (DA) neurons and their target cells can be induced
throughout life and are important determinants of individual differences in susceptibility to …

Canonical BMP–Smad signalling promotes neurite growth in rat midbrain dopaminergic neurons

SV Hegarty, LM Collins, AM Gavin, SL Roche… - Neuromolecular …, 2014 - Springer
Ventral midbrain (VM) dopaminergic (DA) neurons project to the dorsal striatum via the
nigrostriatal pathway to regulate voluntary movements, and their loss leads to the motor …

Genome-wide association study of antibody response to Newcastle disease virus in chicken

C Luo, H Qu, J Ma, J Wang, C Li, C Yang, X Hu, N Li… - BMC genetics, 2013 - Springer
Background Since the first outbreak in Indonesia in 1926, Newcastle disease has become
one of the most common and contagious bird diseases throughout the world. To date …