Bacterial outer membrane vesicles as a platform for biomedical applications: An update

M Li, H Zhou, C Yang, Y Wu, X Zhou, H Liu… - Journal of Controlled …, 2020 - Elsevier
Outer membrane vesicles (OMVs) are produced by Gram-negative bacteria both in vitro and
in vivo. OMVs are nano-sized spherical vehicles formed by lipid bilayer membranes and …

The application of the CRISPR-Cas system in antibiotic resistance

S Tao, H Chen, N Li, W Liang - Infection and drug resistance, 2022 - Taylor & Francis
The emergence and global epidemic of antimicrobial resistance (AMR) poses a serious
threat to global public health in recent years. AMR genes are shared between bacterial …

Considerations for the analysis of bacterial membrane vesicles: methods of vesicle production and quantification can influence biological and experimental outcomes

NJ Bitto, L Zavan, EL Johnston, TP Stinear… - Microbiology …, 2021 - Am Soc Microbiol
Bacterial membrane vesicles (BMVs) are produced by all bacteria and facilitate a range of
functions in host-microbe interactions and pathogenesis. Quantification of BMVs is a critical …

Comparative Analysis of Outer Membrane Vesicle Isolation Methods With an Escherichia coli tolA Mutant Reveals a Hypervesiculating Phenotype With Outer-Inner …

SL Reimer, DR Beniac, SL Hiebert, TF Booth… - Frontiers in …, 2021 - frontiersin.org
Outer membrane vesicles (OMVs) produced by Gram-negative bacteria are mediators of cell
survival and pathogenesis by facilitating virulence factor dissemination and resistance to …

Protocol for serum exosomal miRNAs analysis in prostate cancer patients treated with radiotherapy

B Malla, DM Aebersold, A Dal Pra - Journal of translational medicine, 2018 - Springer
Background Circulating exosomes from prostate cancer (PCa) patients undergoing
radiotherapy are attractive candidate biomarkers for monitoring treatment response. Multiple …

Small-medium extracellular vesicles and their miRNA cargo in retinal health and degeneration: mediators of homeostasis, and vehicles for targeted gene therapy

Y Wooff, AV Cioanca, JA Chu-Tan… - Frontiers in Cellular …, 2020 - frontiersin.org
Photoreceptor cell death and inflammation are known to occur progressively in retinal
degenerative diseases such as age-related macular degeneration (AMD). However, the …

[HTML][HTML] Spontaneously released Neisseria meningitidis outer membrane vesicles as vaccine platform: production and purification

MJH Gerritzen, MLM Salverda, DE Martens, RH Wijffels… - Vaccine, 2019 - Elsevier
Outer membrane vesicles (OMVs) are nanoparticles produced by Gram-negative bacteria
that can be used as vaccines. The application of OMVs as vaccine component can be …

Phosphorylated tau in cerebrospinal fluid-derived extracellular vesicles in Alzheimer's disease: a pilot study

R Sattarov, M Havers, C Orbjörn, E Stomrud… - Scientific Reports, 2024 - nature.com
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder characterized by
brain aggregation of β-amyloid (Aβ) peptides and phosphorylated tau (P-tau) proteins …

An AIE‐active probe for efficient detection and high‐throughput identification of outer membrane vesicles

F Wang, PY Ho, C Kam, Q Yang, J Liu, W Wang… - …, 2023 - Wiley Online Library
Rapid detection and quantification of outer membrane vesicle (OMV) are of both scientific
value and clinical implications. However, limited tools are available for investigations of …

Bacterial growth stage determines the yields, protein composition, and periodontal pathogenicity of Porphyromonas gingivalis outer membrane vesicles

H Mao, T Gong, Y Sun, S Yang, X Qiao… - Frontiers in Cellular and …, 2023 - frontiersin.org
Introduction P. gingivalis (W83), as the keystone pathogen in chronic periodontitis, has been
found to be tightly bound to systemic diseases. Outer membrane vesicles (OMVs) produced …