Antimicrobial peptide-based materials: Opportunities and challenges

A Rai, R Ferrão, P Palma, T Patricio… - Journal of Materials …, 2022 - pubs.rsc.org
The multifunctional properties of antimicrobial peptides (AMPs) make them attractive
candidates for the treatment of various diseases. AMPs are considered as alternatives to …

Bacterial adherence and biofilm formation on medical implants: a review

S Veerachamy, T Yarlagadda… - Proceedings of the …, 2014 - journals.sagepub.com
Biofilms are a complex group of microbial cells that adhere to the exopolysaccharide matrix
present on the surface of medical devices. Biofilm-associated infections in the medical …

Quaternized chitosan as an antimicrobial agent: antimicrobial activity, mechanism of action and biomedical applications in orthopedics

H Tan, R Ma, C Lin, Z Liu, T Tang - International journal of molecular …, 2013 - mdpi.com
Chitosan (CS) is a linear polysaccharide with good biodegradability, biocompatibility and
antimicrobial activity, which makes it potentially useful for biomedical applications, including …

Bone biomaterials for overcoming antimicrobial resistance: Advances in non-antibiotic antimicrobial approaches for regeneration of infected osseous tissue

JM Sadowska, KJ Genoud, DJ Kelly, FJ O'Brien - Materials Today, 2021 - Elsevier
Eliminating bacterial infection and simultaneously providing a bioactive environment for
bone growth during treatment of severe osteomyelitis is one of the greatest global …

Immobilized antibiotics to prevent orthopaedic implant infections

NJ Hickok, IM Shapiro - Advanced drug delivery reviews, 2012 - Elsevier
Many surgical procedures require the placement of an inert or tissue-derived implant deep
within the body cavity. While the majority of these implants do not become colonized by …

Soft tissue integration versus early biofilm formation on different dental implant materials

B Zhao, HC Van Der Mei, G Subbiahdoss, J de Vries… - Dental materials, 2014 - Elsevier
Objective Dental implants anchor in bone through a tight fit and osseo-integratable
properties of the implant surfaces, while a protective soft tissue seal around the implants …

Differential response of Staphylococci and osteoblasts to varying titanium surface roughness

Y Wu, JP Zitelli, KS TenHuisen, X Yu, MR Libera - Biomaterials, 2011 - Elsevier
The surface roughness of metallic orthopaedic implants has typically been used to influence
osseointegration and spatially control load transfer to the surrounding bone. Because of the …

Antibacterial efficacy of iron‐oxide nanoparticles against biofilms on different biomaterial surfaces

M Thukkaram, S Sitaram, S Kannaiyan… - International Journal …, 2014 - Wiley Online Library
Biofilm growth on the implant surface is the number one cause of the failure of the implants.
Biofilms on implant surfaces are hard to eliminate by antibiotics due to the protection offered …

An in vitro assessment of titanium functionalized with polysaccharides conjugated with vascular endothelial growth factor for enhanced osseointegration and inhibition …

X Hu, KG Neoh, Z Shi, ET Kang, C Poh, W Wang - Biomaterials, 2010 - Elsevier
The long-term success of orthopedic implants may be compromised by defective
osseointegration and bacterial infection. An effective approach to minimize implant failure …

Antibacterial designs for implantable medical devices: Evolutions and challenges

H Cao, S Qiao, H Qin, KD Jandt - Journal of Functional Biomaterials, 2022 - mdpi.com
The uses of implantable medical devices are safer and more common since sterilization
methods and techniques were established a century ago; however, device-associated …