Expansion of the Clostridium perfringens toxin-based typing scheme

JI Rood, V Adams, J Lacey, D Lyras, BA McClane… - Anaerobe, 2018 - Elsevier
Clostridium perfringens causes many different histotoxic and enterotoxic diseases in
humans and animals as a result of its ability to produce potent protein toxins, many of which …

An update on the human and animal enteric pathogen Clostridium perfringens

R Kiu, LJ Hall - Emerging microbes & infections, 2018 - Taylor & Francis
Clostridium perfringens, a rapid-growing pathogen known to secrete an arsenal of> 20
virulent toxins, has been associated with intestinal diseases in both animals and humans …

Pathogenicity and virulence of Clostridium perfringens

I Mehdizadeh Gohari, M A. Navarro, J Li, A Shrestha… - Virulence, 2021 - Taylor & Francis
Clostridium perfringens is an extremely versatile pathogen of humans and livestock, causing
wound infections like gas gangrene (clostridial myonecrosis), enteritis/enterocolitis …

Mechanisms of Action and Cell Death Associated with Clostridium perfringens Toxins

MA Navarro, BA McClane, FA Uzal - Toxins, 2018 - mdpi.com
Clostridium perfringens uses its large arsenal of protein toxins to produce histotoxic,
neurologic and intestinal infections in humans and animals. The major toxins involved in …

Avian Pathogenic Escherichia coli and Clostridium perfringens: Challenges in No Antibiotics Ever Broiler Production and Potential Solutions

CA Fancher, L Zhang, AS Kiess, PA Adhikari, TTN Dinh… - Microorganisms, 2020 - mdpi.com
United States is the largest producer and the second largest exporter of broiler meat in the
world. In the US, broiler production is largely converting to antibiotic-free programs which …

Fecal Transplant and Bifidobacterium Treatments Modulate Gut Clostridium Bacteria and Rescue Social Impairment and Hippocampal BDNF Expression in a Rodent …

S Abuaish, NM Al-Otaibi, TS Abujamel, SA Alzahrani… - Brain Sciences, 2021 - mdpi.com
Autism is associated with gastrointestinal dysfunction and gut microbiota dysbiosis,
including an overall increase in Clostridium. Modulation of the gut microbiota is suggested to …

Role of Clostridium perfringens Necrotic Enteritis B-like Toxin in Disease Pathogenesis

KW Lee, HS Lillehoj - Vaccines, 2021 - mdpi.com
Necrotic enteritis (NE) is a devastating enteric disease caused by Clostridium perfringens
type A/G that impacts the global poultry industry by compromising the performance, health …

Probing Genomic Aspects of the Multi-Host Pathogen Clostridium perfringens Reveals Significant Pangenome Diversity, and a Diverse Array of Virulence Factors

R Kiu, S Caim, S Alexander, P Pachori… - Frontiers in …, 2017 - frontiersin.org
Clostridium perfringens is an important cause of animal and human infections, however
information about the genetic makeup of this pathogenic bacterium is currently limited. In this …

Molecular Characterization of Clostridium perfringens Strains Isolated in Italy

K Forti, L Ferroni, M Pellegrini, D Cruciani… - Toxins, 2020 - mdpi.com
Clostridium (C.) perfringens is the causative agent of several diseases and enteric infections
in animals and humans. The pathogenicity of the bacterium is largely mediated by the …

Large-Scale Genomic Analyses and Toxinotyping of Clostridium perfringens Implicated in Foodborne Outbreaks in France

A Mahamat Abdelrahim, N Radomski… - Frontiers in …, 2019 - frontiersin.org
Clostridium perfringens is both an ubiquitous environmental bacterium and the fourth most
common causative agent of foodborne outbreaks (FBOs) in France and Europe. These …