Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

Acinetobacter baumannii biofilms: effects of physicochemical factors, virulence, antibiotic resistance determinants, gene regulation, and future antimicrobial treatments

EC Eze, HY Chenia, ME El Zowalaty - Infection and drug …, 2018 - Taylor & Francis
Acinetobacter baumannii is a leading cause of nosocomial infections due to its increased
antibiotic resistance and virulence. The ability of A. baumannii to form biofilms contributes to …

Designing of a multi-epitope vaccine against the structural proteins of marburg virus exploiting the immunoinformatics approach

SA Sami, KKS Marma, S Mahmud, MAN Khan… - ACS …, 2021 - ACS Publications
Marburg virus disease (MVD) caused by the Marburg virus (MARV) generally appears with
flu-like symptoms and leads to severe hemorrhagic fever. It spreads via direct contact with …

Designing a Recombinant Vaccine against Providencia rettgeri Using Immunoinformatics Approach

S Gul, S Ahmad, A Ullah, S Ismail, M Khurram… - Vaccines, 2022 - mdpi.com
Antibiotic resistance (AR) is the resistance mechanism pattern in bacteria that evolves over
some time, thus protecting the bacteria against antibiotics. AR is due to bacterial evolution to …

Immunoinformatics-Aided Design and Evaluation of a Potential Multi-Epitope Vaccine against Klebsiella Pneumoniae

HA Dar, T Zaheer, M Shehroz, N Ullah, K Naz… - Vaccines, 2019 - mdpi.com
Klebsiella pneumoniae is an opportunistic gram-negative bacterium that causes nosocomial
infection in healthcare settings. Despite the high morbidity and mortality rate associated with …

Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii

M Ud-Din, A Albutti, A Ullah, S Ismail, S Ahmad… - International Journal of …, 2022 - mdpi.com
Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action
of antibiotics used against them. AR is rising to a high level across the globe, and novel …

Immuno-informatics profiling of monkeypox virus cell surface binding protein for designing a next generation multi-valent peptide-based vaccine

M Yousaf, S Ismail, A Ullah, S Bibi - Frontiers in Immunology, 2022 - frontiersin.org
Monkeypox is a viral etiological agent with hallmarks analogous to those observed in
smallpox cases in the past. The ongoing outbreak of Monkeypox viral infection is becoming …

Immunoinformatics characterization of SARS-CoV-2 spike glycoprotein for prioritization of epitope based multivalent peptide vaccine

S Ismail, S Ahmad, SS Azam - Journal of Molecular Liquids, 2020 - Elsevier
The COVID-19 pandemic caused by SARS-CoV-2 is a public health emergency of
international concern and thus calling for the development of effective and safe therapeutics …

Integrated core proteomics, subtractive proteomics, and immunoinformatics investigation to unveil a potential multi-epitope vaccine against schistosomiasis

A Rehman, S Ahmad, F Shahid, A Albutti… - Vaccines, 2021 - mdpi.com
Schistosomiasis is a parasitic infection that causes considerable morbidity and mortality in
the world. Infections of parasitic blood flukes, known as schistosomes, cause the disease …

Pan-genome analysis of oral bacterial pathogens to predict a potential novel multi-epitopes vaccine candidate

T Rida, S Ahmad, A Ullah, S Ismail… - International Journal of …, 2022 - mdpi.com
Porphyromonas gingivalis is a Gram-negative anaerobic bacterium, mainly present in the
oral cavity and causes periodontal infections. Currently, no licensed vaccine is available …