Summary tRNA is the most extensively modified RNA in cells. On average, a bacterial tRNA
contains 8 modifications per molecule and a eukaryotic tRNA contains 13 modifications per …

Chromatin remodeling is essential to allow full development of alternative gene expression
programs in response to environmental changes. In fission yeast, oxidative stress triggers …

Transcript elongation by RNA polymerase II (RNAPII) is dynamic and highly regulated,
thereby contributing to the implementation of gene expression programs during plant …

Many proteins remain poorly characterized even in well-studied organisms, presenting a
bottleneck for research. We applied phenomics and machine-learning approaches with …

Quiescent cells require a continuous supply of proteins to maintain protein homeostasis. In
fission yeast, entry into quiescence is triggered by nitrogen stress, leading to the inactivation …

Both catalase and peroxiredoxin show high activities of H2O2 decomposition and coexist in
the same organism; however, their division of labor in defense against H2O2 is unclear. We …

Candida glabrata is an opportunistic fungal pathogen and the second most prevalent
species isolated from candidiasis patients. C. glabrata has intrinsic tolerance to antifungal …

Aging is characterized by a number of hallmarks including loss of mitochondrial
homeostasis and decay in stress tolerance, among others. Unicellular eukaryotes have …

Candida glabrata (C glabrata) is an important yeast of industrial and medical significance.
Resistance to oxidative stress is an important trait affecting its robustness as a production …

Antisense (as) lncRNAs can regulate gene expression but the underlying mechanisms and
the different cofactors involved remain unclear. Using Native Elongating Transcript …