Rationale Premature infants exposed to oxygen are at risk for bronchopulmonary dysplasia
(BPD), which is characterised by lung growth arrest. Inflammation is important, but the …

Air pollution (AirP) is associated with many neurodevelopmental and neurological disorders
in human populations. Rodent models show similar neurotoxic effects of AirP particulate …

Substantial evidence suggests that pepper consumption is associated with a reduced risk of
obesity-related complications. However, whether piperine, the main component of pepper …

Osteoarthritis (OA) is marked by chronic low-grade systemic inflammation and cartilage
destruction. High fat diet causes obesity and increases the risk of knee OA-development …

A large body of research has established diabetes-related cognitive deterioration,
sometimes known as “diabetic encephalopathy”. Current evidence supports that oxidative …

Under chronic stress, cells must balance competing demands between cellular survival and
tissue function. In metabolic dysfunction-associated steatotic liver disease (MASLD, formerly …

Background Epidemiologic studies suggest that fruit and vegetable (F&V) consumption is
inversely associated with incidence of cardiovascular disease (CVD). However, evidence for …

Hyperandrogenemia plays a critical role in reproductive and metabolic function in females
and is the hallmark of polycystic ovary syndrome. Developing a lean PCOS-like mouse …

Type 2 diabetes mellitus increases the risk of sporadic Alzheimer's disease (sAD), and
antidiabetic drugs, including the sodium–glucose cotransporter inhibitors (SGLTI), are being …

Clinical pathology testing for investigative or biomedical research and for preclinical toxicity
and safety assessment in laboratory animals is a distinct specialty requiring an …