Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches

P Düsing, A Zietzer, PR Goody, MR Hosen… - Journal of molecular …, 2021 - Springer
Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney
disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor …

Albuminuria and Heart Failure: JACC State-of-the-Art Review

MS Khan, I Shahid, SD Anker, GC Fonarow… - Journal of the American …, 2023 - jacc.org
Although chronic kidney disease is characterized by low glomerular filtration rate (GFR) or
albuminuria, estimated GFR (eGFR) is more widely utilized as a marker of risk profile in …

Uremic toxins: an alarming danger concerning the cardiovascular system

CA Falconi, CVC Junho, F Fogaça-Ruiz… - Frontiers in …, 2021 - frontiersin.org
The kidneys and heart share functions with the common goal of maintaining homeostasis.
When kidney injury occurs, many compounds, the so-called “uremic retention solutes” or …

Clinical epidemiology of infectious disease among patients with chronic kidney disease

J Ishigami, K Matsushita - Clinical and experimental nephrology, 2019 - Springer
Infectious disease is recognized as an important complication among patients with end-
stage renal disease, contributing to excess morbidity and health care costs. However, recent …

New potential biomarkers for chronic kidney disease management—A review of the literature

I Lousa, F Reis, I Beirão, R Alves, L Belo… - International Journal of …, 2020 - mdpi.com
The prevalence of chronic kidney disease (CKD) is increasing worldwide, and the mortality
rate continues to be unacceptably high. The biomarkers currently used in clinical practice …

Impact of obesity in kidney diseases

V Kotsis, F Martinez, C Trakatelli, J Redon - Nutrients, 2021 - mdpi.com
The clinical consequences of obesity on the kidneys, with or without metabolic
abnormalities, involve both renal function and structures. The mechanisms linking obesity …

Dietary phosphorus intake and the kidney

AR Chang, C Anderson - Annual review of nutrition, 2017 - annualreviews.org
Although phosphorus is an essential nutrient required for multiple physiological functions,
recent research raises concerns that high phosphorus intake could have detrimental effects …

The cardiovascular burden in end-stage renal disease

M Cozzolino, A Galassi, F Pivari, P Ciceri… - Expanded …, 2017 - karger.com
It is well documented that chronic kidney disease patients have an extremely high risk of
developing cardiovascular (CV) disease (CVD) compared to the general population …

Triglyceride-glucose index is prospectively associated with chronic kidney disease progression in Type 2 diabetes–mediation by pigment epithelium-derived factor

S Low, S Pek, A Moh, K Ang, J Khoo… - Diabetes and …, 2022 - journals.sagepub.com
Background Triglyceride-glucose (TyG) index is a surrogate marker of insulin resistance. Its
role in chronic kidney disease (CKD) progression in Type 2 Diabetes Mellitus (T2DM) is …

Frail hypertensive older adults with prediabetes and chronic kidney disease: insights on organ damage and cognitive performance-preliminary results from the …

G Santulli, V Visco, M Ciccarelli, MNV Ferrante… - Cardiovascular …, 2024 - Springer
Background Hypertension and chronic kidney disease (CKD) pose significant public health
challenges, sharing intertwined pathophysiological mechanisms. Prediabetes is recognized …