[HTML][HTML] Fish toxicity testing for identification of thyroid disrupting chemicals

ZC Dang, M Arena, A Kienzler - Environmental Pollution, 2021 - Elsevier
Identification of thyroid disrupting chemicals (TDCs), one of the most studied types of
endocrine disruptors (EDs), is required according to EU regulations on industrial chemicals …

[HTML][HTML] Changes in fish sex ratio as a basis for regulating endocrine disruptors

ZC Dang, A Kienzler - Environment International, 2019 - Elsevier
Fish sex ratio (SR) is an endpoint potentially indicating both endocrine activity and adversity,
essential elements for identifying Endocrine Disrupting Chemicals (EDCs) as required by …

Chronic paternal/maternal exposure to environmental concentrations of imidacloprid and thiamethoxam causes intergenerational toxicity in zebrafish offspring

JG Zhang, W Shi, DD Ma, ZJ Lu, SY Li… - Environmental …, 2023 - ACS Publications
Imidacloprid (IMI) and thiamethoxam (THM) are ubiquitous in aquatic ecosystems. Their
negative effects on parental fish are investigated while intergenerational effects at …

[HTML][HTML] Disruption of zebrafish sex differentiation by emerging contaminants hexafluoropropylene oxides at environmental concentrations via antagonizing androgen …

T Lu, W Zheng, F Hu, X Lin, R Tao, M Li… - Environment International, 2024 - Elsevier
As alternatives of perfluorooctanoic acid (PFOA), hexafluoropropylene oxide dimeric acid
(HFPO-DA) and trimeric acid (HFPO-TA) have been detected increasingly in environmental …

Deiodinase inhibition impairs the formation of the three posterior swim bladder tissue layers during early embryonic development in zebrafish

I Van Dingenen, L Vergauwen, AC Haigis… - Aquatic Toxicology, 2023 - Elsevier
Thyroid hormone system disruption (THSD) negatively affects multiple developmental
processes and organs. In fish, inhibition of deiodinases, which are enzymes crucial for (in) …

Thyroid hormone actions on male reproductive system of teleost fish

A Tovo-Neto, M da Silva Rodrigues, HR Habibi… - General and …, 2018 - Elsevier
Thyroid hormones (THs) play important roles in the regulation of many biological processes
of vertebrates, such as growth, metabolism, morphogenesis and reproduction. An increasing …

Sex-specific differences in zebrafish brains

G Zhai, J Jia, C Bereketoglu, Z Yin, A Pradhan - Biology of sex Differences, 2022 - Springer
In this systematic review, we highlight the differences between the male and female
zebrafish brains to understand their differentiation and their use in studying sex-specific …

Development of the integrated fish endocrine disruptor test—Part B: Implementation of thyroid‐related endpoints

L Gölz, P Pannetier, T Fagundes… - Integrated …, 2024 - Wiley Online Library
Given the vital role of thyroid hormones (THs) in vertebrate development, it is essential to
identify chemicals that interfere with the TH system. Whereas, among nonmammalian …

Development of the integrated fish endocrine disruptor test (iFEDT)—Part A: Merging of existing fish test guidelines

P Pannetier, L Gölz… - Integrated …, 2024 - Wiley Online Library
There has been increasing interest in endocrine‐disrupting chemicals (EDCs) among
scientists and public authorities over the last 30 years, notably because of their wide use …

[HTML][HTML] Zebrafish cyp17a1 knockout reveals that androgen-mediated signaling is important for male brain sex differentiation

T Shu, G Zhai, A Pradhan, PE Olsson, Z Yin - General and comparative …, 2020 - Elsevier
Brain sex differentiation is a complex process, wherein genes and steroid hormones act to
induce specific gender brain differentiation. Testosterone (T) derived from the gonads has …