[HTML][HTML] Regulation of antiviral immune response by African swine fever virus (ASFV)
X Zheng, S Nie, WH Feng - Virologica Sinica, 2022 - Elsevier
African swine fever (ASF) is a highly contagious and acute hemorrhagic viral disease with a
high mortality approaching 100% in domestic pigs. ASF is an endemic in countries in sub …
high mortality approaching 100% in domestic pigs. ASF is an endemic in countries in sub …
Cytokines in oncolytic virotherapy
Tumors represent a hostile environment for the effector cells of cancer immunosurveillance.
Immunosuppressive receptors and soluble or membrane-bound ligands are abundantly …
Immunosuppressive receptors and soluble or membrane-bound ligands are abundantly …
pMGF505-7R determines pathogenicity of African swine fever virus infection by inhibiting IL-1β and type I IFN production
J Li, J Song, L Kang, L Huang, S Zhou, L Hu… - PLoS …, 2021 - journals.plos.org
Inflammatory factors and type I interferons (IFNs) are key components of host antiviral innate
immune responses, which can be released from the pathogen-infected macrophages …
immune responses, which can be released from the pathogen-infected macrophages …
Interleukin-1β induces mtDNA release to activate innate immune signaling via cGAS-STING
LD Aarreberg, K Esser-Nobis, C Driscoll, A Shuvarikov… - Molecular cell, 2019 - cell.com
Summary Interleukin-1 beta (IL-1β) is a pleiotropic mediator of inflammation and is produced
in response to a wide range of stimuli. During infection, IL-1β production occurs in parallel …
in response to a wide range of stimuli. During infection, IL-1β production occurs in parallel …
Deletion of the H240R Gene of African Swine Fever Virus Decreases Infectious Progeny Virus Production Due to Aberrant Virion Morphogenesis and Enhances …
P Zhou, LF Li, K Zhang, B Wang, L Tang, M Li… - Journal of …, 2022 - Am Soc Microbiol
African swine fever virus (ASFV) is a complex nucleocytoplasmic large DNA virus that
causes African swine fever, a lethal hemorrhagic disease that currently threatens the pig …
causes African swine fever, a lethal hemorrhagic disease that currently threatens the pig …
Current understanding of West Nile virus clinical manifestations, immune responses, neuroinvasion, and immunotherapeutic implications
F Bai, EA Thompson, PJS Vig, AA Leis - Pathogens, 2019 - mdpi.com
West Nile virus (WNV) is the most common mosquito-borne virus in North America. WNV-
associated neuroinvasive disease affects all ages, although elderly and …
associated neuroinvasive disease affects all ages, although elderly and …
Granulocyte macrophage colony-stimulating factor has come of age: From a vaccine adjuvant to antiviral immunotherapy
M Petrina, J Martin, S Basta - Cytokine & growth factor reviews, 2021 - Elsevier
GM-CSF acts as a pro-inflammatory cytokine and a key growth factor produced by several
immune cells such as macrophages and activated T cells. In this review, we discuss recent …
immune cells such as macrophages and activated T cells. In this review, we discuss recent …
Overview on chikungunya virus infection: from epidemiology to state-of-the-art experimental models
LEC Constant, BF Rajsfus, PH Carneiro… - Frontiers in …, 2021 - frontiersin.org
Chikungunya virus (CHIKV) is currently one of the most relevant arboviruses to public
health. It is a member of the Togaviridae family and alphavirus genus and causes an …
health. It is a member of the Togaviridae family and alphavirus genus and causes an …
IL-36 family cytokines in protective versus destructive inflammation
Y Han, A Huard, J Mora, P da Silva, B Brüne… - Cellular Signalling, 2020 - Elsevier
The IL-1 family of cytokines and receptors are critical regulators of inflammation. Within the
IL-1 family and in contrast to its IL-1 and IL-18 subfamilies, the IL-36 subfamily is still poorly …
IL-1 family and in contrast to its IL-1 and IL-18 subfamilies, the IL-36 subfamily is still poorly …
[HTML][HTML] Leaked genomic and mitochondrial DNA contribute to the host response to noroviruses in a STING-dependent manner
The cGAS-STING pathway is central to the interferon response against DNA viruses.
However, recent studies are increasingly demonstrating its role in the restriction of some …
However, recent studies are increasingly demonstrating its role in the restriction of some …