The multiscale physics of cilia and flagella

W Gilpin, MS Bull, M Prakash - Nature Reviews Physics, 2020 - nature.com
Cilia and flagella are fundamental units of motion in cellular biology. These beating, hair-like
organelles share a common basic structure but maintain widely varying functions in systems …

Microscopic artificial cilia–a review

T ul Islam, Y Wang, I Aggarwal, Z Cui, HE Amirabadi… - Lab on a Chip, 2022 - pubs.rsc.org
Cilia are microscopic hair-like external cell organelles that are ubiquitously present in
nature, also within the human body. They fulfill crucial biological functions: motile cilia …

Magnetic cilia carpets with programmable metachronal waves

H Gu, Q Boehler, H Cui, E Secchi, G Savorana… - Nature …, 2020 - nature.com
Metachronal waves commonly exist in natural cilia carpets. These emergent phenomena,
which originate from phase differences between neighbouring self-beating cilia, are …

Dynamics of flexible fibers in viscous flows and fluids

O Du Roure, A Lindner, EN Nazockdast… - Annual Review of …, 2019 - annualreviews.org
The dynamics and deformations of immersed flexible fibers are at the heart of important
industrial and biological processes, induce peculiar mechanical and transport properties in …

Frontiers of chaotic advection

H Aref, JR Blake, M Budišić, SSS Cardoso… - Reviews of Modern …, 2017 - APS
This work reviews the present position of and surveys future perspectives in the physics of
chaotic advection: the field that emerged three decades ago at the intersection of fluid …

A multiscale biophysical model gives quantized metachronal waves in a lattice of beating cilia

B Chakrabarti, S Fürthauer… - Proceedings of the …, 2022 - National Acad Sciences
Motile cilia are slender, hair-like cellular appendages that spontaneously oscillate under the
action of internal molecular motors and are typically found in dense arrays. These active …

Conditions for metachronal coordination in arrays of model cilia

F Meng, RR Bennett, N Uchida… - Proceedings of the …, 2021 - National Acad Sciences
On surfaces with many motile cilia, beats of the individual cilia coordinate to form
metachronal waves. We present a theoretical framework that connects the dynamics of an …

Motile cilia create fluid-mechanical microhabitats for the active recruitment of the host microbiome

JC Nawroth, H Guo, E Koch… - Proceedings of the …, 2017 - National Acad Sciences
We show that mucociliary membranes of animal epithelia can create fluid-mechanical
microenvironments for the active recruitment of the specific microbiome of the host. In …

Spontaneous phase coordination and fluid pumping in model ciliary carpets

AV Kanale, F Ling, H Guo… - Proceedings of the …, 2022 - National Acad Sciences
Ciliated tissues, such as in the mammalian lungs, brains, and reproductive tracts, are
specialized to pump fluid. They generate flows by the collective activity of hundreds of …

Multi-scale spatial heterogeneity enhances particle clearance in airway ciliary arrays

GR Ramirez-San Juan, AJTM Mathijssen, M He, L Jan… - Nature physics, 2020 - nature.com
Mucus clearance constitutes the primary defence of the respiratory system against viruses,
bacteria and environmental insults. This transport across the entire airway emerges from the …