Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Traumatic brain injury (TBI) causes brain damage, which involves primary and secondary
injury mechanisms. Primary injury causes local brain damage, while secondary damage …

Background The indications for intracranial pressure (ICP) monitoring in patients with acute
brain injury and the effects of ICP on patients' outcomes are uncertain. The aims of this study …

Temperature is one of the most fundamental physical properties to characterize various
physical, chemical, and biological processes. Even a slight change in temperature could …

Managing traumatic brain injury (TBI) patients with a cerebral perfusion pressure (CPP) near
to the cerebral autoregulation (CA)-guided “optimal” CPP (CPPopt) value is associated with …

China has more patients with traumatic brain injury (TBI) than most other countries in the
world, making this condition a major public health concern. Population-based mortality of …

Executive summary A concerted effort to tackle the global health problem posed by traumatic
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …

Abstract Prokineticin-2 (Prok2) is an important secreted protein likely involved in the
pathogenesis of several acute and chronic neurological diseases through currently …

Neuropathic pain is a chronic secondary pain condition, which is a consequence of
peripheral or central nervous (somatosensory) system lesions or diseases. It is a devastating …

Current technologies for the point-of-care diagnosis of traumatic brain injury (TBI) lack
sensitivity, require specialist handling or involve complicated and costly procedures. Here …