Background Accumulating studies have revealed that aberrant expression of circular RNAs
(circRNAs) is widely involved in the tumorigenesis and progression of malignant cancers …

This article reviews the dynamic interactions of the tumour microenvironment, highlighting
the roles of acetyl-CoA and melatonergic pathway regulation in determining the interactions …

Abstract Background N4-acetylcytidine (ac4C) as a significant RNA modification has been
reported to maintain the stability of mRNA and to regulate the translation process. However …

Cancer-associated fibroblasts (CAFs) are the most abundant stromal components in the
tumor microenvironment (TME) and closely involved in tumor progression. However, the …

Abstract Background Yin Yang‐1 (YY1) is identified as a transcription factor with multiple
functions. However, the role of YY1 in tumorigenesis remains controversial and its regulatory …

Keloids are an excessive tissue response to dermal damage, characterized by uncontrolled
growth and a high recurrence rate after various treatments. Abnormalities with the …

Objective. Glioblastoma is one of the most common malignant tumors in the brain, and these
glioblastoma patients have very poor prognosis. Ferroptosis is involved in the progression of …

Pancreatic ductal adenocarcinoma (PDAC) is one of most lethal cancers and is projected to
be the second leading cause of cancer deaths in the United States by 2030. The lack of …

Background Glioma is one of the most aggressive malignant brain tumors that is
characterized with inevitably infiltrative growth and poor prognosis. ARST is a novel lncRNA …

Colorectal cancer (CRC) stands as the second most common cause of cancer-related
mortality globally and p53, a widely recognized tumor suppressor, contributes to the …