Thioredoxin-dependent redox regulation of cellular signaling and stress response through reversible oxidation of methionines
DJ Bigelow, TC Squier - Molecular Biosystems, 2011 - pubs.rsc.org
The sensitive oxidations of sulfur containing amino acids (ie, cysteines and methionines)
commonly control protein function, and act as important signaling mechanisms to modify …
commonly control protein function, and act as important signaling mechanisms to modify …
Quantitative mapping of oxidation-sensitive cysteine residues in SERCA in vivo and in vitro by HPLC–electrospray-tandem MS: selective protein oxidation during …
VS Sharov, ES Dremina, NA Galeva… - Biochemical …, 2006 - portlandpress.com
The selective reversible S-glutathiolation of specific SERCA (sarcoplasmic/endoplasmic-
reticulum Ca2+-ATPase) cysteine residues represents a novel physiologic pathway of NO …
reticulum Ca2+-ATPase) cysteine residues represents a novel physiologic pathway of NO …
Calmodulin, conformational states, and calcium signaling. A single-molecule perspective
CK Johnson - Biochemistry, 2006 - ACS Publications
Single-molecule fluorescence measurements can provide a new perspective on the
conformations, dynamics, and interactions of proteins. Recent examples are described …
conformations, dynamics, and interactions of proteins. Recent examples are described …
Revealing Two-State Protein− Protein Interactions of Calmodulin by Single-Molecule Spectroscopy
We report a single-molecule fluorescence resonance energy transfer (FRET) and
polarization study of conformational dynamics of calmodulin (CaM) interacting with a target …
polarization study of conformational dynamics of calmodulin (CaM) interacting with a target …
Redox modulation of cellular metabolism through targeted degradation of signaling proteins by the proteasome
TC Squier - Antioxidants & Redox Signaling, 2006 - liebertpub.com
Under conditions of oxidative stress, the 20S proteasome plays a critical role in maintaining
cellular homeostasis through the selective degradation of oxidized and damaged proteins …
cellular homeostasis through the selective degradation of oxidized and damaged proteins …
Conformational substates of calmodulin revealed by single-pair fluorescence resonance energy transfer: influence of solution conditions and oxidative modification
A calmodulin (CaM) mutant (T34, 110C-CaM) doubly labeled with fluorescence probes
AlexaFluor 488 and Texas Red in opposing domains (CaM-DA) has been used to examine …
AlexaFluor 488 and Texas Red in opposing domains (CaM-DA) has been used to examine …
Site-specific methionine oxidation in calmodulin affects structural integrity and interaction with Ca2+/calmodulin-dependent protein kinase II
Methionine oxidation in the ubiquitous calcium signaling protein calmodulin (CaM) is known
to disrupt downstream signaling and target CaM for proteasomal degradation. The …
to disrupt downstream signaling and target CaM for proteasomal degradation. The …
Structural uncoupling between opposing domains of oxidized calmodulin underlies the enhanced binding affinity and inhibition of the plasma membrane Ca-ATPase
B Chen, MU Mayer, TC Squier - Biochemistry, 2005 - ACS Publications
Stabilization of the plasma membrane Ca-ATPase (PMCA) in an inactive conformation upon
oxidation of multiple methionines in the calcium regulatory protein calmodulin (CaM) is part …
oxidation of multiple methionines in the calcium regulatory protein calmodulin (CaM) is part …
Mediating molecular recognition by methionine oxidation: conformational switching by oxidation of methionine in the carboxyl-terminal domain of calmodulin
A Anbanandam, RJ Bieber Urbauer, RK Bartlett… - Biochemistry, 2005 - ACS Publications
The C-terminus of calmodulin (CaM) functions as a sensor of oxidative stress, with oxidation
of methionine 144 and 145 inducing a nonproductive association of the oxidized CaM with …
of methionine 144 and 145 inducing a nonproductive association of the oxidized CaM with …
[图书][B] Biomedical nanosensors
JM Irudayaraj - 2012 - books.google.com
This book draws together recent data on both cytoplasmic and flagellar dyneins and the
proteins they interact with, to give the reader a clear picture of what is currently known about …
proteins they interact with, to give the reader a clear picture of what is currently known about …