Abstract The updated International Consensus Classification (ICC) of B-acute lymphoblastic
leukemia (B-ALL) and T-acute lymphoblastic leukemia (T-ALL) includes both revisions to …

Structural alterations of NUTM1 were originally thought to be restricted to poorly
differentiated carcinomas with variable squamous differentiation originating in the midline …

Abstract KMT2A-rearranged infant ALL is an aggressive childhood leukemia with poor
prognosis. Here, we investigated the developmental state of KMT2A-rearranged infant B-cell …

Fusions of NUTM1 (15q14) define a novel subtype of B-cell precursor acute lymphoblastic
leukemia (B-ALL) that is mutually exclusive with sentinel leukemia-driving aberrations based …

NUT carcinoma and thoracic SMARCA4‐deficient undifferentiated tumour are unique
entities in the 5th edition of the World Health Organisation (WHO) Classification of Thoracic …

B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is characterized by genetic
alterations with high heterogeneity. Precise subtypes with distinct genomic and/or gene …

NUTM1 gene rearrangements were originally identified in NUT carcinoma. Recently,
NUTM1 has been discovered to rearrange with a variety of gene partners in malignancies of …

Nuclear protein of testis (NUT), a protein product of the NUTM1 gene (located on the long
arm of chromosome 15) with highly restricted physiologic expression in post-meiotic …

Progress in our understanding of the pathogenesis and diagnosis of soft tissue neoplasia is
exceptionally rapid. Although the most recent World Health Organization classification of soft …

Although immune therapy can improve the treatment of clear cell renal cell carcinoma
(ccRCC) significantly, there are still a large proportion of ccRCC patients who progress to …