Background: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive syndromes is a significant determinant of short-and long-term outcomes. Although …
J Hester, C Ventetuolo, T Lahm - Comprehensive Physiology, 2019 - ncbi.nlm.nih.gov
Pulmonary hypertension (PH) encompasses a syndrome of diseases that are characterized by elevated pulmonary artery pressure and pulmonary vascular remodeling and that …
Z Dai, M Li, J Wharton, MM Zhu, YY Zhao - Circulation, 2016 - Am Heart Assoc
Background—Vascular occlusion and complex plexiform lesions are hallmarks of the pathology of severe pulmonary arterial hypertension (PAH) in patients. However, the …
Pulmonary arterial hypertension (PAH) is no longer an orphan disease. There are three different classes of drugs for the treatment of PAH that are currently being used and an …
LA Shimoda, SS Laurie - Journal of molecular medicine, 2013 - Springer
Pulmonary hypertension is a complex, progressive condition arising from a variety of genetic and pathogenic causes. Patients present with a spectrum of histologic and …
SC Pugliese, JM Poth, MA Fini… - … of Physiology-Lung …, 2015 - journals.physiology.org
Hypoxic pulmonary hypertension (PH) comprises a heterogeneous group of diseases sharing the common feature of chronic hypoxia-induced pulmonary vascular remodeling …
N Singh, P Dorfmüller, OA Shlobin… - Circulation …, 2022 - Am Heart Assoc
Pulmonary hypertension (PH) because of chronic lung disease is categorized as Group 3 PH in the most recent classification system. Prevalence of these diseases is increasing over …
Y Kimishima, T Misaka, T Yokokawa, K Wada… - Nature …, 2021 - nature.com
Pulmonary hypertension (PH) is a progressive cardiopulmonary disease characterized by pulmonary arterial remodeling. Clonal somatic mutations including JAK2 V617F, the most …