On the integration of space, time, and memory

H Eichenbaum - Neuron, 2017 - cell.com
The hippocampus is famous for mapping locations in spatially organized environments, and
several recent studies have shown that hippocampal networks also map moments in …

Time cells in the hippocampus: a new dimension for mapping memories

H Eichenbaum - Nature Reviews Neuroscience, 2014 - nature.com
Recent studies have revealed the existence of hippocampal neurons that fire at successive
moments in temporally structured experiences. Several studies have shown that such …

The role of the hippocampus in navigation is memory

H Eichenbaum - Journal of neurophysiology, 2017 - journals.physiology.org
There is considerable research on the neurobiological mechanisms within the hippocampal
system that support spatial navigation. In this article I review the literature on navigational …

Space, time, and episodic memory: The hippocampus is all over the cognitive map

AD Ekstrom, C Ranganath - Hippocampus, 2018 - Wiley Online Library
In recent years, the field has reached an impasse between models suggesting that the
hippocampus is fundamentally involved in spatial processing and models suggesting that …

Space is a latent sequence: A theory of the hippocampus

RV Raju, JS Guntupalli, G Zhou, C Wendelken… - Science …, 2024 - science.org
Fascinating phenomena such as landmark vector cells and splitter cells are frequently
discovered in the hippocampus. Without a unifying principle, each experiment seemingly …

Memory and space: towards an understanding of the cognitive map

D Schiller, H Eichenbaum, EA Buffalo… - Journal of …, 2015 - Soc Neuroscience
More than 50 years of research have led to the general agreement that the hippocampus
contributes to memory, but there has been a major schism among theories of hippocampal …

The CLDN5 gene at the blood-brain barrier in health and disease

Y Hashimoto, C Greene, A Munnich… - Fluids and Barriers of the …, 2023 - Springer
The CLDN5 gene encodes claudin-5 (CLDN-5) that is expressed in endothelial cells and
forms tight junctions which limit the passive diffusions of ions and solutes. The blood–brain …

Spatial goal coding in the hippocampal formation

N Nyberg, É Duvelle, C Barry, HJ Spiers - Neuron, 2022 - cell.com
The mammalian hippocampal formation contains several distinct populations of neurons
involved in representing self-position and orientation. These neurons, which include place …

Hippocampal replay is not a simple function of experience

AS Gupta, MAA Van Der Meer, DS Touretzky… - Neuron, 2010 - cell.com
Replay of behavioral sequences in the hippocampus during sharp wave ripple complexes
(SWRs) provides a potential mechanism for memory consolidation and the learning of …

Internally generated cell assembly sequences in the rat hippocampus

E Pastalkova, V Itskov, A Amarasingham, G Buzsaki - Science, 2008 - science.org
A long-standing conjecture in neuroscience is that aspects of cognition depend on the
brain's ability to self-generate sequential neuronal activity. We found that reliably and …