Positron emission tomography (PET) plays key roles in drug discovery and development, as
well as medical imaging. However, there is a dearth of efficient and simple radiolabeling …

Canataxpropellane belongs to the medicinally important taxane diterpene family. The most
prominent congener, Taxol, is one of the most commonly used anticancer agent in clinics …

A facile and enantioselective approach toward 3, 4-dihydroisocoumarin was developed. The
method involved an amino-thiocarbamate catalyzed enantioselective bromocyclization of …

Stereoselective oxylactonization of ortho-alkenylbenzoate with chiral hypervalent iodine is
applied to the asymmetric synthesis of 4-oxyisochroman-1-one polyketide metabolites …

Catalytic C (sp3)–H functionalization has afforded great opportunities to prepare organic
substances, facilitating the derivatization of complex drugs and natural molecules. This letter …

Catalytic fluorolactonisations of aromatic carboxylic acids have been developed. The
reactions proceed under mild conditions using the commercially available reagent …

In this study we used sequential catalysis PPh3-catalyzed nucleophilic addition followed
by Pd (0)-catalyzed Heck cyclization to construct complex functionalized alkylidene …

In this study, the enantioselective oxylactonization of ortho‐alk‐1‐enylbenzoates with chiral
hypervalent iodine (III) reagents yielded 3‐alkyl‐4‐hydroxyisochroman‐1‐ones with high …

The stereochemical determination of the potent respiratory chain inhibitors ajudazols A and
B and the total synthesis of ajudazol B are reported. Configurational assignment was …

Hypoxylon species are distributed worldwide and have been isolated from different habitats.
The endophyte Hypoxylon anthochroum strain Gseg1 was isolated from healthy leaves of …