Core‐Alkynylated Fluorescent Flippers: Altered Ultrafast Photophysics to Track Thick Membranes

KKP Pamungkas, I Fureraj, L Assies… - Angewandte Chemie …, 2024 - Wiley Online Library
Fluorescent flippers have been introduced as small‐molecule probes to image membrane
tension in living systems. This study describes the design, synthesis, spectroscopic and …

Asparagusic Golgi Trackers

S Saidjalolov, XX Chen, J Moreno, M Cognet… - JACS Au, 2024 - ACS Publications
Thiol-mediated uptake (TMU) is thought to occur through dynamic covalent cascade
exchange networks. Here we show that the cascade accounting for TMU of asparagusic acid …

Single-Molecule Localization Microscopy and Tracking with a Fluorescent Mechanosensitive Probe

J Maillard, E Grassin, E Bestsennaia… - The Journal of …, 2024 - ACS Publications
A milestone in optical imaging of mechanical forces in cells has been the development of the
family of flipper fluorescent probes able to report membrane tension noninvasively in living …

Fluorescent Membrane Probes Obey the Israelachvili Rules

F Bayard, S Matile - Helvetica Chimica Acta, 2024 - Wiley Online Library
When developing fluorescent membrane probes, we naturally tend to focus on the
fluorophore itself. In this study, we show that sometimes it can be beneficial to shift attention …

Actin dynamics sustains spatial gradients of membrane tension in adherent cells

JM Garcia-Arcos, A Mehidi, JS Velázquez, P Guillamat… - bioRxiv, 2024 - biorxiv.org
Tension propagates in lipid bilayers over hundreds of microns within milliseconds,
precluding the formation of tension gradients. Nevertheless, plasma membrane tension …