Triggering biological processes: methods and applications of photocaged peptides and proteins

AE Mangubat-Medina, ZT Ball - Chemical Society Reviews, 2021 - pubs.rsc.org
There has been a significant push in recent years to deploy fundamental knowledge and
methods of photochemistry toward biological ends. Photoreactive groups have enabled …

ESIPT-, AIE-, and AIE+ ESIPT-based light-activated drug delivery systems and bioactive donors for targeted disease treatment

AK Singh, AV Nair, SS Shah, S Ray… - Journal of Medicinal …, 2023 - ACS Publications
Targeted release of bioactive molecules for therapeutic purposes is a key area in the
biomedical field that is growing quickly, where bioactive molecules are released passively or …

[HTML][HTML] Targeted cancer therapy using compounds activated by light

P Dunkel, J Ilaš - Cancers, 2021 - mdpi.com
Simple Summary Cancer is among the leading causes of death, and cancer therapy suffers
from many drawbacks, the lack of selectivity being most noteworthy. In this review, we …

[HTML][HTML] Two-photon uncaging of bioactive compounds: Starter guide to an efficient IR light switch

M Klausen, M Blanchard-Desce - Journal of Photochemistry and …, 2021 - Elsevier
Triggering physiological responses with a light switch has become a reality with the
development of smart molecular probes such as photolabile protecting groups (PPGs), able …

Design and synthesis of two-photon responsive chromophores for near-infrared light-induced uncaging reactions

M Abe, Y Chitose, S Jakkampudi, PTT Thuy, Q Lin… - …, 2017 - thieme-connect.com
Near-infrared two-photon (TP)-induced photorelease (uncaging) of bioactive molecules
such as drugs has attracted considerable attention because of its ability to elucidate …

One-and two-photon uncaging of carbon monoxide (co) with real-time monitoring: on-demand carbazole-based dual co-releasing platform to test over single and …

Y Venkatesh, V Vangala, R Mengji… - Journal of Medicinal …, 2022 - ACS Publications
Herein, we report three new metal-free, photochemically active single, dual, and
combinatorial CORMs (photoCORMs) based on a carbazole-fused 1, 3-dioxol-2-one moiety …

Dual photo-controlled release system for fipronil and dinotefuran

W Fu, K Du, Z Xu, J Cheng, Z Li, X Shao - Photochemical & Photobiological …, 2023 - Springer
Abstract Development of controlled release system promises a huge impact on the pesticide
delivery, which has raised attentions in improving efficacy of pesticides. Herein, the …

Bimane: A visible light induced fluorescent photoremovable protecting group for the single and dual release of carboxylic and amino acids

A Chaudhuri, Y Venkatesh, KK Behara… - Organic letters, 2017 - ACS Publications
A series of ester conjugates of carboxylic and amino acids were synthesized based on
bimane fluorescent photoremovable protecting group (FPRPG). The photorelease of single …

One-and two-photon-activated cysteine persulfide donors for biological targeting

A Chaudhuri, Y Venkatesh, J Das… - The Journal of …, 2019 - ACS Publications
Persulfides have been considered as potential signaling compounds similar to the H2S in “S-
persulfidation”, a sulfur-mediated redox cycle. The research of this sulfur-mediated species …

Photo-uncaging of BODIPY oxime ester for histone deacetylases induced apoptosis in tumor cells

K Sambath, T Zhao, Z Wan, Y Zhang - Chemical Communications, 2019 - pubs.rsc.org
A new class of BODIPY-based oxime ester photo-uncaging group was designed to release
carboxylic acids. The mechanism and kinetics of the photo-uncaging procedure were …