Basal transcription factor TFIID connects transcription activation to the assembly of the RNA
polymerase II preinitiation complex at the core promoter of genes. The mechanistic …

Transcription initiation constitutes a major checkpoint in gene regulation across all living
organisms. Control of chromatin function is tightly linked to this checkpoint, which is best …

The frequency of antifungal resistance, particularly to the azole class of ergosterol
biosynthetic inhibitors, is a growing global health problem. Survival rates for those infected …

Long noncoding RNAs (lncRNAs) are emerging as important regulators during
tumorigenesis by serving as competing endogenous RNAs (ceRNAs). In this study, the qRT …

Aspergillus fumigatus is the leading cause of pulmonary fungal diseases. Azoles have been
used for many years as the main antifungal agents to treat and prevent invasive …

Pervasive transcription initiates from cryptic promoters and is observed in eukaryotes
ranging from yeast to mammals. The Set2-Rpd3 regulatory system prevents cryptic promoter …

Down-regulator of transcription 1 (DR1) is a crucial biomarker closely related to Hashimoto's
Thyroiditis (HT). In this study, a highly selective electrochemical biosensor for ultrasensitive …

Genome-wide localization of chromatin and transcription regulators can be detected by a
variety of techniques. Here, we describe a novel method 'greenCUT&RUN'for genome-wide …

Aspergillus fumigatus is the leading cause of pulmonary fungal diseases. Azoles have been
used for many years as the main antifungal agents to treat and prevent invasive …

USP affiliated authors: BARROS, MÁRIO HENRIQUE DE-ICB; GOLDMAN, GUSTAVO
HENRIQUE-FCFRP; FERNÁNDEZ, CLARA ISABEL VALERO-FCFRP; SILVA, PATRÍCIA …