Tissue-specific engineering: 3D bioprinting in regenerative medicine

Z Wang, W Kapadia, C Li, F Lin, RF Pereira… - Journal of Controlled …, 2021 - Elsevier
Despite its complexity, the human body is composed of only four basic tissue types, namely
epithelial, connective, muscular and nervous tissues. Notably, each tissue is an assemblage …

Corneal regeneration using adipose-derived mesenchymal stem cells

JL Alió del Barrio, A De la Mata, MP De Miguel… - Cells, 2022 - mdpi.com
Adipose-derived stem cells are a subtype of mesenchymal stem cell that offers the important
advantage of being easily obtained (in an autologous manner) from low invasive …

Mesenchymal stromal cell–based therapy for dry eye: current status and future perspectives

Y Jiang, S Lin, Y Gao - Cell transplantation, 2022 - journals.sagepub.com
Dry eye is one of the most common chronic diseases in ophthalmology. It affects quality of
life and has become a public health problem that cannot be ignored. The current treatment …

Mesenchymal stromal cells for the treatment of ocular autoimmune diseases

JY Oh, RH Lee - Progress in retinal and eye research, 2021 - Elsevier
Mesenchymal stromal cells, commonly referred to as MSCs, have emerged as a promising
cell-based therapy for a range of autoimmune diseases thanks to several therapeutic …

Factors defining human adipose stem/stromal cell immunomodulation in vitro

M Mahmoud, M Abdel-Rasheed, ER Galal… - Stem Cell Reviews and …, 2024 - Springer
Human adipose tissue-derived stem/stromal cells (hASCs) are adult multipotent
mesenchymal stem/stromal cells with immunomodulatory capacities. Here, we present up-to …

Corneal stroma regeneration: Preclinical studies

JLA Del Barrio, F Arnalich-Montiel… - Experimental Eye …, 2021 - Elsevier
Corneal grafting is one of the most common and successful forms of human tissue
transplantation in the world, but the need for corneal grafting is growing and availability of …

Third-party allogeneic mesenchymal stromal cells prevent rejection in a pre-sensitized high-risk model of corneal transplantation

P Lohan, N Murphy, O Treacy, K Lynch… - Frontiers in …, 2018 - frontiersin.org
High-risk cornea transplant recipients represent a patient population with significant un-met
medical need for more effective therapies to prevent immunological graft rejection due to …

[HTML][HTML] Lentivirus-mediated IL-10-expressing Bone Marrow Mesenchymal Stem Cells promote corneal allograft survival via upregulating lncRNA 003946 in a rat …

X Lu, Y Ru, C Chu, Y Lv, Y Gao, Z Jia, Y Huang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Corneal transplantation is an effective treatment to corneal blindness. However,
the immune rejection imperils corneal allograft survival. An interventional modality is …

Applications of mesenchymal stem cells in ocular surface diseases: sources and routes of delivery

M Soleimani, A Masoumi, B Momenaei… - Expert opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction Mesenchymal stem cells (MSCs) are novel, promising agents for
treating ocular surface disorders. MSCs can be isolated from several tissues and delivered …

The potential role of bioengineering and three-dimensional printing in curing global corneal blindness

PE Ludwig, TJ Huff, JM Zuniga - Journal of Tissue …, 2018 - journals.sagepub.com
An insufficiency of accessible allograft tissue for corneal transplantation leaves many
impaired by untreated corneal disease. There is promise in the field of regenerative …