Eukaryotic core promoters and the functional basis of transcription initiation
Abstract RNA polymerase II (Pol II) core promoters are specialized DNA sequences at
transcription start sites of protein-coding and non-coding genes that support the assembly of …
transcription start sites of protein-coding and non-coding genes that support the assembly of …
Structural basis of transcription initiation by RNA polymerase II
S Sainsbury, C Bernecky, P Cramer - Nature reviews Molecular cell …, 2015 - nature.com
Transcription of eukaryotic protein-coding genes commences with the assembly of a
conserved initiation complex, which consists of RNA polymerase II (Pol II) and the general …
conserved initiation complex, which consists of RNA polymerase II (Pol II) and the general …
Genome-wide analysis of mammalian promoter architecture and evolution
Mammalian promoters can be separated into two classes, conserved TATA box–enriched
promoters, which initiate at a well-defined site, and more plastic, broad and evolvable CpG …
promoters, which initiate at a well-defined site, and more plastic, broad and evolvable CpG …
The RNA polymerase II core promoter
ST Smale, JT Kadonaga - Annual review of biochemistry, 2003 - annualreviews.org
▪ Abstract The events leading to transcription of eukaryotic protein-coding genes culminate
in the positioning of RNA polymerase II at the correct initiation site. The core promoter, which …
in the positioning of RNA polymerase II at the correct initiation site. The core promoter, which …
The general transcription machinery and general cofactors
MC Thomas, CM Chiang - Critical reviews in biochemistry and …, 2006 - Taylor & Francis
In eukaryotes, the core promoter serves as a platform for the assembly of transcription
preinitiation complex (PIC) that includes TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA …
preinitiation complex (PIC) that includes TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA …
Transcription of eukaryotic protein-coding genes
TI Lee, RA Young - Annual review of genetics, 2000 - annualreviews.org
▪ Abstract The past decade has seen an explosive increase in information about regulation
of eukaryotic gene transcription, especially for protein-coding genes. The most striking …
of eukaryotic gene transcription, especially for protein-coding genes. The most striking …
[HTML][HTML] Regulation of gene expression via the core promoter and the basal transcriptional machinery
T Juven-Gershon, JT Kadonaga - Developmental biology, 2010 - Elsevier
The RNA polymerase II core promoter is a structurally and functionally diverse
transcriptional regulatory element. There are two main strategies for transcription initiation …
transcriptional regulatory element. There are two main strategies for transcription initiation …
Structure of promoter-bound TFIID and model of human pre-initiation complex assembly
The general transcription factor IID (TFIID) plays a central role in the initiation of RNA
polymerase II (Pol II)-dependent transcription by nucleating pre-initiation complex (PIC) …
polymerase II (Pol II)-dependent transcription by nucleating pre-initiation complex (PIC) …
The RNA polymerase II core promoter: a key component in the regulation of gene expression
JEF Butler, JT Kadonaga - Genes & development, 2002 - genesdev.cshlp.org
The development, growth, and survival of eukaryotic organisms require the proper
regulation of tens of thousands of genes. By complex formulae that have yet to be solved …
regulation of tens of thousands of genes. By complex formulae that have yet to be solved …
The molecular biology of the CCAAT-binding factor NF-Y
R Mantovani - Gene, 1999 - Elsevier
Protein coding genes are transcribed by Polymerase II, under the control of short discrete
DNA elements in promoters and enhancers, recognized with high efficiency and specificity …
DNA elements in promoters and enhancers, recognized with high efficiency and specificity …