Background: Phosphoinositide 3-kinase (PI3Ks) is a member of intracellular lipid kinases
and involved in the regulation of cellular proliferation, differentiation and survival …

Polysaccharides are an important class of functional phytochemicals, and various studies
have demonstrated the beneficial pharmacological effects of polysaccharides, including …

Resistance to conventional chemotherapeutic agents, including irinotecan (CPT‑11), 5-
fluorouracil and capecitabine is a major cause for therapeutic failure in patients with …

Colon cancer (CC) is the third common neoplasm worldwide, and it is still a big challenge for
exploring new effective medicine for treating CC. Natural product promoting human health …

Daucus carota L., a member of the Apiaceae family, comprises 13 subspecies, with one
being cultivated (D. carota L. ssp. sativus (Hoffm.) Arcang.) and the remaining being wild …

The ring-opening reaction of the two diepoxides, α-himachalenes 6 and 7, with aluminum
lithium hydride (LiAlH 4) in ether produced the title compounds C 15 H 24 O 2 sesquiterpene …

How individuals respond to chronic stress varies. Susceptible individuals ultimately develop
depression; whereas resilient individuals live normally. In this study, our objective was to …

Objectives Nowadays, one of the most common gastrointestinal cancers is colorectal cancer
(CRC). Chemotherapy is still one of the main methods to treat cancer. However, the currently …

Cedrus libani is a majestic evergreen tree native to the Mediterranean mountains of
Lebanon, Syria and Turkey. In this study, the tree heart wood was extracted using hexane to …

The presence of breast cancer stem cells (BCSCs) induces the aggressive progression and
recurrence of breast cancer. These cells are drug resistant, have the capacity to self-renew …