Cargoes of exosomes function as potential biomarkers for Mycobacterium tuberculosis infection

N Wang, Y Yao, Y Qian, D Qiu, H Cao, H Xiang… - Frontiers in …, 2023 - frontiersin.org
Exosomes as double-membrane vesicles contain various contents of lipids, proteins,
mRNAs and non-coding RNAs, and involve in multiple physiological processes, for instance …

Functions of exosomal non-coding RNAs to the infection with Mycobacterium tuberculosis

J Wang, Y Li, N Wang, J Wu, X Ye, Y Jiang… - Frontiers in …, 2023 - frontiersin.org
Tuberculosis (TB) is a major infectious disease induced by Mycobacterium tuberculosis (M.
tb) which causes the world's dominant fatal bacterial contagious disease. Increasing studies …

The dynamics of Mycobacterium tuberculosis phagosome and the fate of infection

Q Zhang, S Ma, P Li, J Xie - Cellular Signalling, 2023 - Elsevier
Phagosomes are vesicles produced by phagocytosis of phagocytes, which are crucial in
immunity against Mycobacterium tuberculosis (Mtb) infection. After the phagocyte ingests the …

The role of Mycobacterium tuberculosis exosomal miRNAs in host pathogen cross-talk as diagnostic and therapeutic biomarkers

F Mukhtar, A Guarnieri, N Brancazio… - Frontiers in …, 2024 - frontiersin.org
Tuberculosis (TB) is a global threat, affecting one-quarter of the world's population. The
World Health Organization (WHO) reports that 6 million people die annually due to chronic …

Diagnostic value of microRNAs in active tuberculosis based on quantitative and enrichment analyses

S Yao, B Liu, X Hu, Y Tan, K Liu, M He, B Wu… - … and Infectious Disease, 2024 - Elsevier
Background Tuberculosis (TB) infection remains a crucial global health challenge, with
active tuberculosis (ATB) representing main infection source. MicroRNA (miRNA) has …

Current landscape of exosomes in tuberculosis development, diagnosis, and treatment applications

X Sun, W Li, L Zhao, K Fan, F Qin, L Shi, F Gao… - Frontiers in …, 2024 - frontiersin.org
Tuberculosis (TB), caused by the bacterial pathogen Mycobacterium tuberculosis (MTB),
remains one of the most prevalent and deadly infectious diseases worldwide. Currently …

[HTML][HTML] Evaluation of miR-let-7f, miR-125a, and miR-125b expression levels in sputum and serum samples of Iranians and Afghans with pulmonary tuberculosis

AN Neamatollahi, S Tarashi… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Materials and Methods: A total of 60 Iranian and Afghan patients with active pulmonary TB
were enrolled in the Pulmonary Department of the Pasteur Institute of Iran. Serum and …

[HTML][HTML] Transport of miR-766–3p to A549 cells by plasma-derived exosomes and its effect on intracellular survival of Mycobacterium tuberculosis by regulating …

X Cui, F Zhang, H Meng, T Yuan, M Li, D Yuan… - Microbiological …, 2025 - Elsevier
Exosomal microRNAs (miRNAs) in circulation were recognized as potential biomarkers for
the diagnosis of multiple diseases. However, its potential as a diagnostic hallmark for …

[HTML][HTML] Exosomal Small RNA Sequencing Profiles in Plasma from Subjects with Latent Mycobacterium tuberculosis Infection

X Cui, H Meng, M Li, X Chen, D Yuan, C Wu - Microorganisms, 2024 - mdpi.com
Despite huge efforts, tuberculosis (TB) is still a major public health threat worldwide, with
approximately 23% of the human population harboring a latent TB infection (LTBI). LTBI can …

Single-cell analysis of the miRNA activities in tuberculous meningitis (TBM) model mice injected with the BCG vaccine

X Zhang, L Pan, P Zhang, L Wang, Y Shen, P Xu… - International …, 2023 - Elsevier
Background Our previous study revealed the transcriptome atlas of specific cell types in
tuberculous meningitis (TBM) model mice injected with the BCG vaccine via scRNA …