Antibodies and neuronal autoimmune disorders of the CNS

F Graus, A Saiz, J Dalmau - Journal of neurology, 2010 - Springer
We review the neuronal antibodies described in CNS disorders in order to clarify their
diagnostic value, emphasize potentials pitfalls and limitations in the diagnosis of …

'Medusa head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 3: anti-Yo/CDR2, anti-Nb/AP3B2, PCA-2, anti-Tr …

S Jarius, B Wildemann - Journal of neuroinflammation, 2015 - Springer
Serological testing for anti-neural autoantibodies is important in patients presenting with
idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine …

Updated diagnostic criteria for paraneoplastic neurologic syndromes

F Graus, A Vogrig, S Muñiz-Castrillo… - Neurology …, 2021 - AAN Enterprises
Objective The contemporary diagnosis of paraneoplastic neurologic syndromes (PNSs)
requires an increasing understanding of their clinical, immunologic, and oncologic …

Association of autoimmune encephalitis with combined immune checkpoint inhibitor treatment for metastatic cancer

TJ Williams, DR Benavides, KA Patrice… - JAMA …, 2016 - jamanetwork.com
Importance Paraneoplastic encephalitides usually precede a diagnosis of cancer and are
often refractory to immunosuppressive therapy. Conversely, autoimmune encephalitides are …

CNS aquaporin-4 autoimmunity in children

A McKeon, VA Lennon, T Lotze, S Tenenbaum… - Neurology, 2008 - AAN Enterprises
Background: In adult patients, autoantibodies targeting the water channel aquaporin-4
(AQP4) are a biomarker for a spectrum of CNS inflammatory demyelinating disorders with …

Adult-onset opsoclonus-myoclonus syndrome

JP Klaas, JE Ahlskog, SJ Pittock… - Archives of …, 2012 - jamanetwork.com
Background Little is known about adult-onset opsoclonus-myoclonus syndrome (OMS)
outside of individual case reports. Objective To describe adult-onset OMS. Design Review of …

Associations between HLA and autoimmune neurological diseases with autoantibodies

S Muñiz-Castrillo, A Vogrig, J Honnorat - Autoimmunity Highlights, 2020 - Springer
Recently, several autoimmune neurological diseases have been defined by the presence of
autoantibodies against different antigens of the nervous system. These autoantibodies have …

Paraneoplastic isolated myelopathy: clinical course and neuroimaging clues

EP Flanagan, A McKeon, VA Lennon, J Kearns… - Neurology, 2011 - AAN Enterprises
Objective: To report the clinical phenotype and outcome of isolated paraneoplastic
myelopathy. Methods: We systematically reviewed clinical, serologic, and MRI data for 31 …

Paraneoplastic neuropathies: what's new since the 2004 recommended diagnostic criteria

M Zoccarato, W Grisold, A Grisold, V Poretto… - Frontiers in …, 2021 - frontiersin.org
The diagnostic criteria published by the PNS (Paraneoplastic Neurological Syndromes)
Euronetwork in 2004 provided a useful classification of PNS, including paraneoplastic …

SOX1 antibodies are markers of paraneoplastic Lambert–Eaton myasthenic syndrome

L Sabater, M Titulaer, A Saiz, J Verschuuren, AO Gure… - Neurology, 2008 - AAN Enterprises
Background/Objective: We reported that 43% of patients with Lambert–Eaton myasthenic
syndrome (LEMS) and small cell lung cancer (SCLC) had an antibody called anti-glial …