The unique properties and characteristics of ocular tissues and the whole set of defence
mechanisms of the ocular globe make the instillation of ocular drugs into a difficult task with …

Chitosan on its own is a well-established natural polymer and is widely regarded as a
biodegradable, biocompatible and nontoxic material for drug delivery applications. Although …

Eye drops are ophthalmic formulations routinely used to treat dry eye. However, the low
ocular bioavailability is an obvious drawback of eye drops owing to short ocular retention …

Different size and morphology monodispersed chitosan (CS) microspheres loaded with the
anticancer drug of 5-fluorouracil (5-Fu) were prepared by the microfluidic method assisted …

This study aimed to develop a suitable buccal mucoadhesive nanoparticle (NP) formulation
containing fluconazole for the local treatment of oral candidiasis. The suitability of the …

The objective of the study was to investigate the potential of montmorillonite as a sustained
carrier in the preparation of drug-loaded nanoparticles for prolonged ocular application …

Frequent instillation of terbinafine hydrochloride (T HCl) eye drops (0.25%, w/v) is necessary
to maintain effective aqueous humor concentrations for treatment of fungal keratitis. The …

Dexamethasone acetate (DEX) and polymyxin B sulfate (polymyxin B) were formulated as a
cationic nanoemulsion for the treatment of ophthalmic infections. As novel concept, the …

This work aimed to develop voriconazole in situ gelling ocular inserts loaded with niosomal
suspension. Niosomes and mixed niosomes were prepared using span 40 and span 60 with …

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