Anorexia in the elderly

JE Morley, AJ Silver - Neurobiology of aging, 1988 - Elsevier
Weight loss and anorexia occur commonly in the elderly. While in many cases the anorexia
can be attributed to associated disease processes, it does appear that a true anorexia of …

The effects of age on pain sensitivity: preclinical studies

RP Yezierski - Pain medicine, 2012 - academic.oup.com
Objective. Preclinical studies of pain and aging represent an area of research where
considerations of age, strain, gender, and method of behavioral assessment are but some of …

Brain and blood biomarkers of tauopathy and neuronal injury in humans and rats with neurobehavioral syndromes following blast exposure

DL Dickstein, R De Gasperi, MA Gama Sosa… - Molecular …, 2021 - nature.com
Traumatic brain injury (TBI) is a risk factor for the later development of neurodegenerative
diseases that may have various underlying pathologies. Chronic traumatic encephalopathy …

Roles of gender, gonadectomy and estrous phase in the analgesic effects of intracerebroventricular morphine in rats

KL Kepler, B Kest, JM Kiefel, ML Cooper… - Pharmacology …, 1989 - Elsevier
Gender and gonadal function have previously been shown to influence the magnitude of
analgesia following systemic morphine and opioid and nonopioid forms of swim analgesia …

Ascending endorphin inhibition of distress vocalization

BH Herman, J Panksepp - Science, 1981 - science.org
Distress vocalizations were produced in adult guinea pigs by electrical stimulation of the
dorsomedial thalamus or the septum-preoptic area. Both of these forebrain-derived …

Age-related reduction of human growth hormone-binding sites in the human brain

Z Lai, P Roos, Q Zhai, Y Olsson, K Fhölenhag… - Brain research, 1993 - Elsevier
Previous studies have shown that alterations in various neuroendocrine functions occur with
increasing age. We here report a study of growth hormone (GH)-binding sites in different …

Opioid use in the elderly

OHG Wilder-Smith - European Journal of Pain, 2005 - Elsevier
Pain treatment in the elderly is an important challenge to Western societies due to
increasing numbers of old persons, their higher incidence of pain, and their greater …

Drugs and sex differences: a review of drugs relating to anaesthesia

GK Ciccone, A Holdcroft - Survey of Anesthesiology, 1999 - journals.lww.com
Drugs and Sex Differences: A Review of Drugs Relating to Ana... : Survey of Anesthesiology
Drugs and Sex Differences: A Review of Drugs Relating to Anaesthesia : Survey of …

Endorphinergic and α-noradrenergic systems in the paraventricular nucleus: effects on eating behavior

SF Leibowitz, L Hor - Peptides, 1982 - Elsevier
Brain cannulated rats were injected with the opioid peptide β-endorphin (β-EP) directly into
the hypothalamic paraventricular nucleus (PVN) where norepinephrine (NE) is most …

Interactions among aging, gender, and gonadectomy effects upon morphine antinociception in rats

AK Islam, ML Cooper, RJ Bodnar - Physiology & Behavior, 1993 - Elsevier
In addition to age-related deficits in morphine antinociception in female rats, gender and
gonadectomy differences have also been observed, with male rats displaying greater …