The effectiveness of L-arginine in clinical conditions associated with hypoxia

N Kurhaluk - International journal of molecular sciences, 2023 - mdpi.com
The review summarises the data of the last 50 years on the effectiveness of the amino acid L-
arginine in therapeutic practice in conditions accompanied by different-origin hypoxia. The …

Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in aging-related disorders

R Benfante, S Di Lascio, S Cardani… - Aging clinical and …, 2021 - Springer
Neuroinflammation and cholinergic dysfunction, leading to cognitive impairment, are
hallmarks of aging and neurodegenerative disorders, including Alzheimer's disease (AD) …

The human-restricted isoform of the α7 nAChR, CHRFAM7A: a double-edged sword in neurological and inflammatory disorders

S Di Lascio, D Fornasari, R Benfante - International Journal of Molecular …, 2022 - mdpi.com
CHRFAM7A is a relatively recent and exclusively human gene arising from the partial
duplication of exons 5 to 10 of the α7 neuronal nicotinic acetylcholine receptor subunit (α7 …

Cholinergic signaling controls immune functions and promotes homeostasis

I Wessler, CJ Kirkpatrick - International Immunopharmacology, 2020 - Elsevier
Acetylcholine (ACh) was created by nature as one of the first signaling molecules,
expressed already in procaryotes. Based on the positively charged nitrogen, ACh could …

Ansofaxine hydrochloride inhibits tumor growth and enhances Anti-TNFR2 in murine colon cancer model

Q Jing, Q Wan, Y Nie, J Luo, X Zhang, L Zhu… - Frontiers in …, 2023 - frontiersin.org
Introduction: As psychoneuroimmunology flourishes, there is compelling evidence that
depression suppresses the anti-tumor immune response, promotes the progression of …

Protective role of acetylcholine and the cholinergic system in the injured heart

CLC Ming, X Wang, C Gentile - Iscience, 2024 - cell.com
This review explores the roles of the cholinergic system in the heart, comprising the
neuronal and non-neuronal cholinergic systems. Both systems are essential for maintaining …

Retinoic acid attenuates nuclear factor kappaB mediated induction of NLRP3 inflammasome

B Purbasari, R Madhyastha, H Madhyastha… - Pharmacological …, 2022 - Springer
Abstract Background Acetylcholine (ACh), a neurotransmitter and a part of the cholinergic
system, can modify immune responses. Expression of acetylcholine receptors (AChR) in …

Diazinon acute exposure induces neutrophil extracellular traps in Nile tilapia (Oreochromis niloticus)

CE Covantes-Rosales, GA Toledo-Ibarra… - Food and Agricultural …, 2020 - Taylor & Francis
Diazinon is an organophosphate insecticide commonly used worldwide to chemically
control different organisms considered as pests. In the past years, diazinon has been …

Persistent immune dysregulation from sepsis in critical care

SJ Cashmore - 2023 - qmro.qmul.ac.uk
Introduction Patients who survive sepsis can develop an increased morbidity and mortality
that persists long-term. This thesis examines whether sepsis induces epigenetic changes in …

[PDF][PDF] Análisis de los efectos antiinflamatorios del bromuro de aclidinio sobre los neutrófilos de pacientes con EPOC: una aproximación a los mecanismos de …

MAC Juan, DJM PAYÁ, DGJ SAMPER, DJC GIMENO - 2023 - webges.uv.es
• Ministerio Español de Economía y Competitividad: PID2020-114871RB-I00• Subvenciones
de la acción estratégica en salud (modalidad proyectos de investigación en salud) del …