Plasmodium—a brief introduction to the parasites causing human malaria and their basic biology

S Sato - Journal of physiological anthropology, 2021 - Springer
Malaria is one of the most devastating infectious diseases of humans. It is problematic
clinically and economically as it prevails in poorer countries and regions, strongly hindering …

Safety and Efficacy of Tafenoquine for Plasmodium vivax Malaria Prophylaxis and Radical Cure: Overview and Perspectives

MB Markus - Therapeutics and Clinical Risk Management, 2021 - Taylor & Francis
This article is inter alia a brief, first-stop guide to possible adverse events (AEs) associated
with tafenoquine (TQ) intake. Safety and efficacy findings for TQ in Plasmodium vivax …

Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype

B Hommel, A Sturny-Leclère, S Volant… - PLoS …, 2019 - journals.plos.org
Metabolically quiescent pathogens can persist in a viable non-replicating state for months or
even years. For certain infectious diseases, such as tuberculosis, cryptococcosis …

Novel insights into Plasmodium vivax therapeutic failure: CYP2D6 activity and time of exposure to malaria modulate the risk of recurrence

ACR Silvino, FS Kano, MA Costa… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
Plasmodium vivax relapse is one of the major causes of sustained global malaria
transmission. Primaquine (PQ) is the only commercial drug available to prevent relapses …

Putative contribution of 8-aminoquinolines to preventing recrudescence of malaria

MB Markus - Tropical Medicine and Infectious Disease, 2023 - mdpi.com
Enhanced therapeutic efficacy achieved in treating Plasmodium vivax malaria with an 8-
aminoquinoline (8-AQ) drug such as primaquine (PQ) together with a partner drug such as …

Impact of host stress on the replication rate of Plasmodium: take it easy to avoid malaria recurrences

R Pigeault, A Ruiz De Paz, M Baur, J Isaïa… - Frontiers in Ecology …, 2023 - frontiersin.org
Malaria is widespread throughout the world and affects many animal species. Although the
origin of this vector-borne disease was discovered more than a century ago, several aspects …

Recurrence patterns and evolution of submicroscopic and asymptomatic Plasmodium vivax infections in malaria-endemic areas of the Peruvian Amazon

SS Garcia Castillo, C Abanto Alvarez… - PLOS Neglected …, 2024 - journals.plos.org
Background In the Peruvian Amazon, Plasmodium vivax malaria transmission is maintained
due to the high frequency of recurrences. By understanding the recurrence rates of …

High Proportion of Genome-Wide Homology and Increased Pretreatment pvcrt Levels in Plasmodium vivax Late Recurrences: a Chloroquine Therapeutic Efficacy …

E Rovira-Vallbona, N Van Hong… - Antimicrobial agents …, 2021 - Am Soc Microbiol
Chloroquine (CQ) is the first-line treatment for Plasmodium vivax malaria in most countries
where malaria is endemic. Monitoring P. vivax CQ resistance (CQR) is critical but remains …

Advancing Key Gaps in the Knowledge of Plasmodium vivax Cryptic Infections Using Humanized Mouse Models and Organs-on-Chips

I Aparici Herraiz, HR Caires… - Frontiers in cellular …, 2022 - frontiersin.org
Plasmodium vivax is the most widely distributed human malaria parasite representing 36.3%
of disease burden in the South-East Asia region and the most predominant species in the …

[HTML][HTML] Suboptimal doses of antimalarials relative to increasing body weight and the risk of plasmodium vivax recurrence in the Republic of Korea Armed Forces …

YH Hwang, D Yoon, S Go, JS Yeom… - Journal of Korean …, 2024 - pmc.ncbi.nlm.nih.gov
Background We aimed to analyze the epidemiology, clinical characteristics, and outcomes
of malaria caused by Plasmodium vivax among military members of the Republic of Korea …