A close look at molecular self-assembly with the transmission electron microscope
Molecular self-assembly is pervasive in the formation of living and synthetic materials.
Knowledge gained from research into the principles of molecular self-assembly drives …
Knowledge gained from research into the principles of molecular self-assembly drives …
New opportunities in transmission electron microscopy of polymers
Recent advances in instrumentation for transmission electron microscopy have pushed the
resolution limit, leading to remarkable instruments capable of imaging at 0.5 Å. But, when …
resolution limit, leading to remarkable instruments capable of imaging at 0.5 Å. But, when …
Structural elucidation of a polypeptoid chain in a crystalline lattice reveals key morphology-directing role of the N-terminus
The ability to engineer synthetic polymers with the same structural precision as
biomacromolecules is crucial to enable the de novo design of robust nanomaterials with …
biomacromolecules is crucial to enable the de novo design of robust nanomaterials with …
Importance of the positively charged σ-hole in crystal engineering of halogenated polypeptoids
Crystalline nanosheets formed by amphiphilic block copolypeptoids with halogenated
phenyl side chains were imaged at the atomic-scale using cryogenic transmission electron …
phenyl side chains were imaged at the atomic-scale using cryogenic transmission electron …
Peptide science: A “rule model” for new generations of peptidomimetics
Peptides have been heavily investigated for their biocompatible and bioactive properties.
Though a wide array of functionalities can be introduced by varying the amino acid …
Though a wide array of functionalities can be introduced by varying the amino acid …
Atomic-resolution imaging of small organic molecules on graphene
P Kharel, BE Janicek, SH Bae, AL Loutris… - Nano …, 2022 - ACS Publications
Here, we demonstrate atomic-resolution scanning transmission electron microscopy (STEM)
imaging of light elements in small organic molecules on graphene. We use low-dose, room …
imaging of light elements in small organic molecules on graphene. We use low-dose, room …
Diblock copolypeptoids: a review of phase separation, crystallization, self-assembly and biological applications
S Xuan, RN Zuckermann - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Polypeptoids are biocompatible, synthetically accessible, chemically and enzymatically
stable, chemically diverse, and structurally controllable. As a bioinspired and biomimetic …
stable, chemically diverse, and structurally controllable. As a bioinspired and biomimetic …
Engineering the atomic structure of sequence-defined peptoid polymers and their assemblies
S Xuan, RN Zuckermann - Polymer, 2020 - Elsevier
Peptoids are a family of sequence-defined, non-natural biomimetic polymers which show
excellent properties including good chemical and enzymatic stability and high structural …
excellent properties including good chemical and enzymatic stability and high structural …
Thermodynamic Driving Forces for the Self-Assembly of Diblock Polypeptoids
Peptoid polymers with sequence-defined side chains are observed to self-assemble into a
variety of structures spanning nanometer and micron scales. We explored a diblock …
variety of structures spanning nanometer and micron scales. We explored a diblock …
Atomic-scale corrugations in crystalline polypeptoid nanosheets revealed by three-dimensional cryogenic electron microscopy
Amphiphilic molecules that can crystallize often form molecularly thin nanosheets in
aqueous solutions. The possibility of atomic-scale corrugations in these structures has not …
aqueous solutions. The possibility of atomic-scale corrugations in these structures has not …