Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

Apolipoprotein (apo) B, the critical structural protein of the atherogenic lipoproteins, has two
major isoforms: apoB48 and apoB100. ApoB48 is found in chylomicrons and chylomicron …

Cardiometabolic diseases are the leading cause of death worldwide. Despite a known
genetic component, our understanding of these diseases remains incomplete. Here, we …

Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …

Intestinal epithelial cells derive from stem cells at the crypt base and travel along the crypt-
villus axis to die at the villus tip. The two dominant villus epithelial cell types, absorptive …

Low density lipoprotein (LDL) is the predominant atherogenic lipoprotein particle in the
circulation. Conventionally, a fasting lipid profile has been used for atherosclerotic …

Polar bears are uniquely adapted to life in the High Arctic and have undergone drastic
physiological changes in response to Arctic climates and a hyperlipid diet of primarily …

Familial hypercholesterolemia (FH) is a genetic disorder resulting from mutations in genes
encoding proteins involved in the metabolism of low density lipoproteins (LDL) and …

Sequence variants affecting blood lipids and coronary artery disease (CAD) may enhance
understanding of the atherogenicity of lipid fractions. Using a large resource of whole …

Familial Hypercholesterolemias: Prevalence, genetics, diagnosis and screening
recommendations from the National Lipid Association Expert Panel on Familial …