Synthesis of Structural ADP-Ribose Analogues as Inhibitors for SARS-CoV-2 Macrodomain 1

KJ Rijpkema, M Schuller, MS van der Veer… - Organic …, 2024 - ACS Publications
Protein adenosine diphosphate (ADP)-ribosylation is crucial for a proper immune response.
Accordingly, viruses have evolved ADP-ribosyl hydrolases to remove these modifications, a …