Introduction: Deep brain stimulation is a safe and effective neurointerventional technique for
the treatment of movement disorders. Electrical stimulation of subcortical structures may …

The midline and intralaminar nuclei of the thalamus form a major part of the “limbic
thalamus;” that is, thalamic structures anatomically and functionally linked with the limbic …

A central challenge of neuroscience is to elucidate how brain function supports
consciousness. Here, we combine the specificity of focal deep brain stimulation with fMRI …

Central thalamus plays a critical role in forebrain arousal and organized behavior. However,
network-level mechanisms that link its activity to brain state remain enigmatic. Here, we …

Up to 20% of pediatric patients with primary generalized epilepsy (PGE) will not respond
effectively to medication for seizure control. Responsive neurostimulation (RNS) is a …

Traumatic brain injury (TBI) is a looming epidemic, growing most rapidly in the elderly
population. Some of the most devastating sequelae of TBI are related to depressed levels of …

Impaired breathing, cardiac function, and arousal during and after seizures are important
causes of morbidity and mortality. Previous work suggests that these changes are …

Introduction One-third of patients with epilepsy continue to have seizures despite
antiepileptic medications. Some of these refractory patients may not be candidates for …

What happens in the human brain when we are unconscious? Despite substantial work, we
are still unsure which brain regions are involved and how they are impacted when …

Impaired consciousness in temporal lobe seizures has a major negative impact on quality of
life. The prevailing view holds that this disorder impairs consciousness by seizure spread to …