Novel Strategies Targeting Mitochondria-Lysosome Contact Sites for the Treatment of Neurological Diseases
Y Xie, S Wenlin, A Han, X Zhou, S Zhang… - Frontiers in Molecular …, 2025 - frontiersin.org
Mitochondria and lysosomes are critical for neuronal homeostasis, as highlighted by their
dysfunction in various neurological diseases. Recent studies have identified dynamic …
dysfunction in various neurological diseases. Recent studies have identified dynamic …
Supramolecular delivery of dinuclear ruthenium and osmium MCU inhibitors
NP Bigham, RJ Novorolsky, KR Davis, H Zou… - Inorganic Chemistry …, 2024 - pubs.rsc.org
The transmembrane protein known as the mitochondrial calcium uniporter (MCU) mediates
the influx of calcium ions (Ca2+) into the mitochondrial matrix. An overload of mitochondrial …
the influx of calcium ions (Ca2+) into the mitochondrial matrix. An overload of mitochondrial …