Chemically modified biomacromolecules─ ie, proteins, nucleic acids, glycans, and lipids─
have become crucial tools in chemical biology. They are extensively used not only to …

Catalysis and medicine are often considered as two independent research fields with their
own respective scientific phenomena. Promoted by recent advances in nanochemistry, large …

As a class of carbon-based nanomaterials, carbon dots (CDs) have attracted enormous
attention because of their tunable optical and physicochemical properties, such as …

Light-powered catalysis has found broad utility as a chemical transformation strategy, with
widespread impact on energy, environment, drug discovery and human health. A noteworthy …

Extracellular deposition of β-amyloid (Aβ) peptide aggregates is a major characteristic of
Alzheimer's disease (AD) brain. Because Aβ peptide aggregates aggravate neuropathy and …

The aberrant aggregation of amyloid-β peptide (Aβ) in the brain has been considered as the
major pathological hallmark of Alzheimer's diseases (AD). Inhibition of Aβ aggregation is …

Protein degradation induced by small molecules by recruiting endogenous protein
degradation systems, such as ubiquitin-proteasome systems, to disease-related proteins is …

C60 has a special dual function; it can act as both a powerful reactive oxygen species (ROS)
producer under UV or visible light and an ROS scavenger in the dark. However, ROS has …

Alzheimer's disease (AD) is a major form of dementia, closely associated with the
filamentous assembly of amyloid-β (Aβ) and Tau protein in the brain, which can cause …

The abnormal self-assembly of amyloid-β protein (Aβ) into toxic aggregates is a major
pathological hallmark of Alzheimer's disease (AD). Modulation of Aβ fibrillization with …