Renal microcirculation injury as the main cause of ischemic acute kidney injury development

E Kwiatkowska, S Kwiatkowski, V Dziedziejko… - Biology, 2023 - mdpi.com
Simple Summary Acute kidney injury can result from multiple factors. The main cause is
reduced renal perfusion. Kidneys are susceptible to ischemia due to the anatomy of …

Acute renal injury events in diabetic patients treated with SGLT2 inhibitors: a comprehensive review with a special reference to RAAS blockers

AJ Scheen, P Delanaye - Diabetes & Metabolism, 2022 - Elsevier
Renin-angiotensin-aldosterone system (RAAS) blockers and sodium-glucose cotransporter
type 2 inhibitors (SGLT2is) are two pharmacological classes that proved a remarkable …

Mortality and cardiovascular events in diabetes mellitus patients at dialysis initiation treated with glucagon-like peptide-1 receptor agonists

HW Lai, CY See, JY Chen, VC Wu - Cardiovascular Diabetology, 2024 - Springer
Abstract Background Glucagon-like Peptide-1 Receptor Agonists (GLP-1RAs) have
demonstrated efficacy in improving mortality and cardiovascular (CV) outcomes. However …

[HTML][HTML] Kidney function decline and serious adverse drug reactions in patients with CKD

SM Laville, V Gras-Champel, A Hamroun… - American Journal of …, 2024 - Elsevier
Rationale & Objective Adverse drug reactions (ADRs) are common in patients with chronic
kidney disease (CKD). The impact of kidney function decline on serious ADR risk has been …

Antihypertensives associated adverse events: a review of mechanisms and pharmacogenomic biomarkers available evidence in multi-ethnic populations

SM Altoum, ZN Al-Mahayri, BR Ali - Frontiers in Pharmacology, 2023 - frontiersin.org
Hypertension remains a significant health burden worldwide, re-emphasizing the
outstanding need for more effective and safer antihypertensive therapeutic approaches …

Renin angiotensin aldosterone inhibitors in the treatment of proteinuria in children with congenital anomalies of the kidney and urinary tract: more evidence needed

G Rivetti, P Gizzone, A Di Sessa… - Expert Review of …, 2023 - Taylor & Francis
Introduction Congenital anomalies of the kidney and urinary tract (CAKUT) can be
associated with proteinuria, possibly leading to a decline in kidney function. The aim of this …

The effects of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in critically ill patients with acute kidney injury: an observational study …

X Zhu, J Xue, Z Liu, W Dai, J Xiang, H Xu… - Frontiers in …, 2022 - frontiersin.org
Background: The safety of prescribing angiotensin-converting enzyme inhibitors (ACEIs)
and angiotensin receptor blockers (ARBs) during acute kidney injury (AKI) remains unclear …

Incidence and transition of acute kidney injury, acute kidney disease to chronic kidney disease after acute type A aortic dissection surgery

CH Chang, SW Chen, JJ Chen, YH Chan… - Journal of Clinical …, 2021 - mdpi.com
Acute kidney disease (AKD) is the persistence of renal injury between days 8 and 90 after
an initial acute kidney injury (AKI). In this study, we aimed to explore the incidence of AKD …

[HTML][HTML] Reducing oxygen demand to alleviate acute kidney injury

X Zhou - Frontiers in Bioscience-Landmark, 2023 - imrpress.com
Maintaining a balance between the supply and demand of oxygen is vital for proper organ
function. Most types of acute kidney injury (AKI) are characterized by hypoxia, a state where …

The role of gut-derived, protein-bound uremic toxins in the cardiovascular complications of acute kidney injury

P Caillard, Y Bennis, I Six, S Bodeau, S Kamel… - Toxins, 2022 - mdpi.com
Acute kidney injury (AKI) is a frequent disease encountered in the hospital, with a higher
incidence in intensive care units. Despite progress in renal replacement therapy, AKI is still …