Radical-involved transition metal (TM) catalysis has greatly enabled new reactivities in
recent decades. Copper-catalyzed radical relay offers enormous potential in C (sp3)–H …

Radical C–H functionalization represents a useful means of streamlining synthetic routes by
avoiding substrate preactivation and allowing access to target molecules in fewer steps. The …

This Perspective presents the fundamental principles, the elementary reactions, the initial
catalytic systems, and the contemporary catalysts that have converted C–H bond …

Copper is one of the most abundant and less toxic transition metals. Nature takes advantage
of the bioavailability and rich redox chemistry of Cu to carry out oxygenase and oxidase …

Chiral allenes are important structural motifs frequently found in natural products,
pharmaceuticals, and other organic compounds. Asymmetric 1, 4-difunctionalization of 1, 3 …

Conspectus Comprising periodically repeating inorganic nodes and organic linkers, metal–
organic frameworks (MOFs) represent a novel class of porous molecular solids with well …

Transition-metal catalysis of substitution reactions of alkyl electrophiles by nitrogen
nucleophiles is beginning to emerge as a powerful strategy for synthesizing higher-order …

Amines are a quintessential moiety in bioactive molecules, pharmaceuticals and organic
materials. Transition-metal-catalysed C–N coupling of aryl electrophiles has been …

Site selectivity represents a key challenge for non-directed C–H functionalization, even
when the C–H bond is intrinsically reactive. Here, we report a copper-catalyzed method for …

Molecular catalysts for ammonia oxidation to dinitrogen represent enabling components to
utilize ammonia as a fuel and/or source of hydrogen. Ammonia oxidation requires not only …