[HTML][HTML] Brain edema formation and therapy after intracerebral hemorrhage

Y Wan, KG Holste, Y Hua, RF Keep, G Xi - Neurobiology of disease, 2023 - Elsevier
Intracerebral hemorrhage (ICH) accounts for about 10% of all strokes in the United States of
America causing a high degree of disability and mortality. There is initial (primary) brain …

The mechanism of ferroptosis in early brain injury after subarachnoid hemorrhage

X Deng, Y Wu, Z Hu, S Wang, S Zhou, C Zhou… - Frontiers in …, 2023 - frontiersin.org
Subarachnoid hemorrhage (SAH) is a cerebrovascular accident with an acute onset, severe
disease characteristics, and poor prognosis. Within 72 hours after the occurrence of SAH, a …

Blood–brain barrier disruption and its involvement in neurodevelopmental and neurodegenerative disorders

A Aragón-González, PJ Shaw, L Ferraiuolo - International journal of …, 2022 - mdpi.com
The blood–brain barrier (BBB) is a highly specialized and dynamic compartment which
regulates the uptake of molecules and solutes from the blood. The relevance of the …

Blood–Brain Barrier Breakdown in Alzheimer's Disease: Mechanisms and Targeted Strategies

AE Alkhalifa, NF Al-Ghraiybah, J Odum… - International Journal of …, 2023 - mdpi.com
The blood–brain barrier (BBB) is a unique and selective feature of the central nervous
system's vasculature. BBB dysfunction has been observed as an early sign of Alzheimer's …

[HTML][HTML] Aquaporin-4 in glymphatic system, and its implication for central nervous system disorders

S Peng, J Liu, C Liang, L Yang, G Wang - Neurobiology of Disease, 2023 - Elsevier
The clearance function is essential for maintaining brain tissue homeostasis, and the
glymphatic system is the main pathway for removing brain interstitial solutes. Aquaporin-4 …

[Retracted] Aquaporin 4 Depolarization‐Enhanced Transferrin Infiltration Leads to Neuronal Ferroptosis after Subarachnoid Hemorrhage in Mice

Y Liu, Z Wang, C Cao, Z Xu, J Lu… - Oxidative Medicine …, 2022 - Wiley Online Library
The infiltration of blood components into the brain parenchyma through the lymphoid system
is an important cause of subarachnoid hemorrhage injury. AQP4, a water channel protein …

Involvement of Astrocytes in the Formation, Maintenance, and Function of the Blood–Brain Barrier

G Schiera, CM Di Liegro, G Schirò, G Sorbello… - Cells, 2024 - mdpi.com
The blood–brain barrier (BBB) is a fundamental structure that protects the composition of the
brain by determining which ions, metabolites, and nutrients are allowed to enter the brain …

Role of astrocytes in sleep deprivation: accomplices, resisters, or bystanders?

M Que, Y Li, X Wang, G Zhan, X Luo… - Frontiers in Cellular …, 2023 - frontiersin.org
Sleep plays an essential role in all studied animals with a nervous system. However, sleep
deprivation leads to various pathological changes and neurobehavioral problems …

The hallmark and crosstalk of immune cells after intracerebral hemorrhage: Immunotherapy perspectives

W Zhang, Q Wu, S Hao, S Chen - Frontiers in Neuroscience, 2023 - frontiersin.org
Intracerebral hemorrhage (ICH) is one of the most dangerous types of strokes with a high
morbidity and mortality rate. Currently, the treatment of ICH is not well developed, mainly …

Single-cell transcriptomics reveals evidence of endothelial dysfunction in the brains of COVID-19 patients with implications for glioblastoma progression

A Thakur, L Liang, S Banerjee, K Zhang - Brain sciences, 2023 - mdpi.com
Background: Endothelial dysfunction is implicated in various inflammatory diseases such as
ischemic stroke, heart attack, organ failure, and COVID-19. Recent studies have shown that …