Coupling of mechanical deformation and electromagnetic fields in biological cells

M Torbati, K Mozaffari, L Liu, P Sharma - Reviews of Modern Physics, 2022 - APS
The cell, as the most fundamental unit of life, is a microcosm of biology in which the
confluence of nearly all aspects of classical physics (mechanics, statistical physics …

Technologies for measuring red blood cell deformability

K Matthews, ES Lamoureux, ME Myrand-Lapierre… - Lab on a Chip, 2022 - pubs.rsc.org
Human red blood cells (RBCs) are approximately 8 μm in diameter, but must repeatedly
deform through capillaries as small as 2 μm in order to deliver oxygen to all parts of the …

Microfluidic deformability cytometry: A review

Y Chen, K Guo, L Jiang, S Zhu, Z Ni, N Xiang - Talanta, 2023 - Elsevier
Cell deformability plays an important role in cellular processes and functions, including cell
growth and differentiation, as well as cell transfer and cell cycle. Measuring deformability at …

Mechanical fatigue of human red blood cells

Y Qiang, J Liu, M Dao, S Suresh… - Proceedings of the …, 2019 - National Acad Sciences
Fatigue arising from cyclic straining is a key factor in the degradation of properties of
engineered materials and structures. Fatigue can also induce damage and fracture in …

Determination of dielectric properties of cells using AC electrokinetic-based microfluidic platform: a review of recent advances

W Liang, X Yang, J Wang, Y Wang, W Yang, L Liu - Micromachines, 2020 - mdpi.com
Cell dielectric properties, a type of intrinsic property of cells, can be used as
electrophysiological biomarkers that offer a label-free way to characterize cell phenotypes …

High shear stress amplitude in combination with prolonged stimulus duration determine induction of osteoclast formation by hematopoietic progenitor cells

C Bratengeier, A Liszka, J Hoffman… - The FASEB …, 2020 - Wiley Online Library
To date, it is unclear how fluid dynamics stimulate mechanosensory cells to induce an
osteoprotective or osteodestructive response. We investigated how murine hematopoietic …

Label-free microfluidics for single-cell analysis

Y Chen, Z Zhou, S Zhu, Z Ni, N Xiang - Microchemical Journal, 2022 - Elsevier
Accurate analysis of the mechanical, electrical, and optical properties of single cells can
provide useful information on their physiological and pathological states. Microfluidics has …

Dielectrophoresis separation of platelets using a novel zigzag microchannel

Y Guan, Y Liu, H Lei, S Liu, F Xu, X Meng, M Bai… - Micromachines, 2020 - mdpi.com
Platelet separation and purification are required in many applications including in the
detection and treatment of hemorrhagic and thrombotic diseases, in addition to transfusions …

Dielectric spectroscopy of red blood cells in sickle cell disease

J Liu, Y Qiang, E Du - Electrophoresis, 2021 - Wiley Online Library
Hypoxia‐induced polymerization of sickle hemoglobin and the related ion diffusion across
cell membrane can lead to changes in cell dielectric properties, which can potentially serve …

Electrical impedance characterization of erythrocyte response to cyclic hypoxia in sickle cell disease

J Liu, Y Qiang, O Alvarez, E Du - ACS sensors, 2019 - ACS Publications
Cell sickling is the process in which intracellular polymerization of deoxygenated sickle
hemoglobin (HbS) leads to distorted, rigid cells, resulting in abnormal blood rheology and …