Minocycline attenuates lipopolysaccharide-induced locomotor deficit and anxiety-like behavior and related expression of the BDNF/CREB protein in the rat medial …
Neuroinflammation following lipopolysaccharide (LPS) administration induces locomotor
deficits and anxiety-like behaviour. In this study, minocycline was compared to memantine …
deficits and anxiety-like behaviour. In this study, minocycline was compared to memantine …
Loss of the zinc receptor ZnR/GPR39 in mice enhances anxiety-related behavior and motor deficits, and modulates KCC2 expression in the amygdala
R Sagi, M Chakraborty, M Bogdanovic, H Asraf… - Behavioral and Brain …, 2024 - Springer
Background Mood disorders, particularly depression and anxiety, are associated with zinc
dyshomeostasis and aberrant GABAergic signaling. Activation of ZnR/GPR39 by synaptic …
dyshomeostasis and aberrant GABAergic signaling. Activation of ZnR/GPR39 by synaptic …
[HTML][HTML] Memantine suppresses the excitotoxicity but fails to rescue the ataxic phenotype in SCA1 model mice
OS Belozor, A Vasilev, AG Mileiko, LD Mosina… - Biomedicine & …, 2024 - Elsevier
Abstract Spinocerebellar ataxia type 1 (SCA1) is a debilitating neurodegenerative disorder
of the cerebellum and brainstem. Memantine has been proposed as a potential treatment for …
of the cerebellum and brainstem. Memantine has been proposed as a potential treatment for …