High-speed AFM and applications to biomolecular systems
Directly observing individual protein molecules in action at high spatiotemporal resolution
has long been a holy grail for biological science. This is because we long have had to infer …
has long been a holy grail for biological science. This is because we long have had to infer …
High-Speed Atomic Force Microscopy Reveals Rotary Catalysis of Rotorless F1-ATPase
F1 is an adenosine triphosphate (ATP)–driven motor in which three torque-generating β
subunits in the α3β3 stator ring sequentially undergo conformational changes upon ATP …
subunits in the α3β3 stator ring sequentially undergo conformational changes upon ATP …
A therapeutic connection between dietary phytochemicals and ATP synthase
For centuries, phytochemicals have been used to prevent and cure multiple health ailments.
Phytochemicals have been reported to have antioxidant, antidiabetic, antitussive …
Phytochemicals have been reported to have antioxidant, antidiabetic, antitussive …
Structural basis of redox modulation on chloroplast ATP synthase
In higher plants, chloroplast ATP synthase has a unique redox switch on its γ subunit that
modulates enzyme activity to limit ATP hydrolysis at night. To understand the molecular …
modulates enzyme activity to limit ATP hydrolysis at night. To understand the molecular …
Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F1–Fo coupling
Mitochondrial adenosine triphosphate (ATP) synthase uses the proton gradient across the
inner mitochondrial membrane to synthesize ATP. Structural and single molecule studies …
inner mitochondrial membrane to synthesize ATP. Structural and single molecule studies …
Load-dependent destabilization of the γ-rotor shaft in FOF1 ATP synthase revealed by hydrogen/deuterium-exchange mass spectrometry
FoF1 is a membrane-bound molecular motor that uses proton-motive force (PMF) to drive
the synthesis of ATP from ADP and Pi. Reverse operation generates PMF via ATP …
the synthesis of ATP from ADP and Pi. Reverse operation generates PMF via ATP …
Role of the DELSEED loop in torque transmission of F1-ATPase
M Tanigawara, KV Tabata, Y Ito, J Ito, R Watanabe… - Biophysical journal, 2012 - cell.com
F 1-ATPase is an ATP-driven rotary motor that generates torque at the interface between the
catalytic β-subunits and the rotor γ-subunit. The β-subunit inwardly rotates the C-terminal …
catalytic β-subunits and the rotor γ-subunit. The β-subunit inwardly rotates the C-terminal …
Aerobic growth of Escherichia coli is reduced, and atp synthesis is selectively inhibited when five C-terminal residues are deleted from the ϵ subunit of ATP synthase
F-type ATP synthases are rotary nanomotor enzymes involved in cellular energy metabolism
in eukaryotes and eubacteria. The ATP synthase from Gram-positive and-negative model …
in eukaryotes and eubacteria. The ATP synthase from Gram-positive and-negative model …
Energy status of kiwifruit stored under different temperatures or exposed to long-term anaerobic conditions or pure oxygen
Z Huang, L Guo, H Wang, H Qu, S Ma, Y Liu… - Postharvest biology and …, 2014 - Elsevier
Energy status is a key factor switching on ripening and senescence of fruit. In this study,
kiwifruit was stored at 15° C or 25° C or exposed to long-term N 2 and O 2. Energy …
kiwifruit was stored at 15° C or 25° C or exposed to long-term N 2 and O 2. Energy …
[HTML][HTML] Investigation of the Mechanism of Action of AMPs from Amphibians to Identify Bacterial Protein Targets for Therapeutic Applications
C Canè, L Tammaro, A Duilio, A Di Somma - Antibiotics, 2024 - mdpi.com
Antimicrobial peptides (AMPs) from amphibians represent a promising source of novel
antibacterial agents due to their potent and broad-spectrum antimicrobial activity, which …
antibacterial agents due to their potent and broad-spectrum antimicrobial activity, which …