Beyond population‐level targets for drug concentrations: precision dosing needs individual‐level targets that include superior biomarkers of drug responses
TM Polasek, RW Peck - Clinical Pharmacology & Therapeutics, 2024 - Wiley Online Library
The purpose of precision dosing is to increase the chances of therapeutic success in
individual patients. This is achieved in practice by adjusting doses to reach precision dosing …
individual patients. This is achieved in practice by adjusting doses to reach precision dosing …
[HTML][HTML] Barriers to global pharmacometrics: educational challenges and opportunities across the globe
During the past three decades, pharmacometrics has developed considerably and gained
recognition globally and across disciplines, causing the demand of well-trained …
recognition globally and across disciplines, causing the demand of well-trained …
[HTML][HTML] Model-informed drug discovery and development approaches to inform clinical trial design and regulatory decisions: A primer for the MENA region
MS Alasmari, S Albusaysi, M Elhefnawy, AM Ali… - Saudi Pharmaceutical …, 2024 - Elsevier
Abstract Model-Informed Drug Discovery and Development (MID3) represents a
transformative approach in pharmaceutical research, integrating quantitative models to …
transformative approach in pharmaceutical research, integrating quantitative models to …
What “Impact” Do NLME Publications Have Outside Our Community?
S Hennig, J Fischer, C Kloft - CPT: Pharmacometrics & Systems …, 2020 - Wiley Online Library
The number of publications applying nonlinear mixed‐effect (NLME) modeling has
increased yearly since its first appearance in 1979. Here, we evaluated articles that have …
increased yearly since its first appearance in 1979. Here, we evaluated articles that have …