Applications of CRISPR/Cas13-based RNA editing in plants
The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-
associated (Cas) system is widely used as a genome-editing tool in various organisms …
associated (Cas) system is widely used as a genome-editing tool in various organisms …
[HTML][HTML] The double life of CRISPR–Cas13
JF Bot, J van der Oost, N Geijsen - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•CRISPR–Cas13 is potentially capable of collateral RNA cleavage in eukaryotic
cells.•Target RNA levels, cell size, and cell-type-specific properties may influence the …
cells.•Target RNA levels, cell size, and cell-type-specific properties may influence the …
Detect and destroy: CRISPR-based technologies for the response against viruses
CA Freije, PC Sabeti - Cell host & microbe, 2021 - cell.com
Despite numerous viral outbreaks in the last decade, including a devastating global
pandemic, diagnostic and therapeutic technologies remain severely lacking. CRISPR-Cas …
pandemic, diagnostic and therapeutic technologies remain severely lacking. CRISPR-Cas …
Applications of the versatile CRISPR‐Cas13 RNA targeting system
M Kordyś, R Sen, Z Warkocki - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
CRISPR‐Cas are adaptable natural prokaryotic defense systems that act against invading
viruses and plasmids. Among the six currently known major CRISPR‐Cas types, the type VI …
viruses and plasmids. Among the six currently known major CRISPR‐Cas types, the type VI …
Functional features and current applications of the RNA‐targeting type VI CRISPR‐Cas systems
V Perčulija, J Lin, B Zhang, S Ouyang - Advanced Science, 2021 - Wiley Online Library
CRISPR‐Cas systems are a form of prokaryotic adaptive immunity that employs RNA‐
guided endonucleases (Cas effectors) to cleave foreign genetic elements. Due to their …
guided endonucleases (Cas effectors) to cleave foreign genetic elements. Due to their …
Silencing RNAs expressed from W-linked PxyMasc “retrocopies” target that gene during female sex determination in Plutella xylostella
T Harvey-Samuel, X Xu… - Proceedings of the …, 2022 - National Acad Sciences
The Lepidoptera are an insect order of cultural, economic, and environmental importance,
representing∼ 10% of all described living species. Yet, for all but one of these species …
representing∼ 10% of all described living species. Yet, for all but one of these species …
Efficient sex separation by exploiting differential alternative splicing of a dominant marker in Aedes aegypti
Only female mosquitoes consume blood giving them the opportunity to transmit deadly
human pathogens. Therefore, it is critical to remove females before conducting releases for …
human pathogens. Therefore, it is critical to remove females before conducting releases for …
The application of CRISPR/Cas systems for antiviral therapy
HJE Baddeley, M Isalan - Frontiers in Genome Editing, 2021 - frontiersin.org
As CRISPR/Cas systems have been refined over time, there has been an effort to apply
them to real world problems, such as developing sequence-targeted antiviral therapies …
them to real world problems, such as developing sequence-targeted antiviral therapies …
Efficient inhibition of HIV using CRISPR/Cas13d nuclease system
H Nguyen, H Wilson, S Jayakumar, V Kulkarni… - Viruses, 2021 - mdpi.com
Recently discovered Clustered Regularly Interspaced Short Palindromic Repeats
(CRISPR)/Cas13 proteins are programmable RNA-guided ribonucleases that target single …
(CRISPR)/Cas13 proteins are programmable RNA-guided ribonucleases that target single …
CRISPR-Cas and CRISPR-based screening system for precise gene editing and targeted cancer therapy
Target cancer therapy has been developed for clinical cancer treatment based on the
discovery of CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system …
discovery of CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system …