Obesity I: Overview and molecular and biochemical mechanisms

RH Lustig, D Collier, C Kassotis, TA Roepke… - Biochemical …, 2022 - Elsevier
Obesity is a chronic, relapsing condition characterized by excess body fat. Its prevalence
has increased globally since the 1970s, and the number of obese and overweight people is …

[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Environmental obesogens: mechanisms and controversies

JJ Heindel, B Blumberg - Annual review of pharmacology and …, 2019 - annualreviews.org
Obesity is a worldwide pandemic in adults as well as children and adds greatly to health
care costs through its association with type 2 diabetes, metabolic syndrome, cardiovascular …

Meal frequency and timing in health and disease

MP Mattson, DB Allison, L Fontana… - Proceedings of the …, 2014 - National Acad Sciences
Although major research efforts have focused on how specific components of foodstuffs
affect health, relatively little is known about a more fundamental aspect of diet, the frequency …

Time to consider the “exposome hypothesis” in the development of the obesity pandemic

V Catalán, I Avilés-Olmos, A Rodríguez, S Becerril… - Nutrients, 2022 - mdpi.com
The obesity epidemic shows no signs of abatement. Genetics and overnutrition together with
a dramatic decline in physical activity are the alleged main causes for this pandemic. While …

An economy of scales: A selective review of obesity's economic causes, consequences, and solutions

J Cawley - Journal of health economics, 2015 - Elsevier
This paper reviews the economic research on obesity, covering topics such as the
measurement of, and trends in, obesity, the economic causes of obesity (eg the monetary …

Hidden shift of the ionome of plants exposed to elevated CO2 depletes minerals at the base of human nutrition

I Loladze - elife, 2014 - elifesciences.org
Mineral malnutrition stemming from undiversified plant-based diets is a top global challenge.
In C3 plants (eg, rice, wheat), elevated concentrations of atmospheric carbon dioxide …

Role of environmental chemicals in diabetes and obesity: a National Toxicology Program workshop review

KA Thayer, JJ Heindel, JR Bucher… - Environmental health …, 2012 - ehp.niehs.nih.gov
Background: There has been increasing interest in the concept that exposures to
environmental chemicals may be contributing factors to the epidemics of diabetes and …

Obesogens: a unifying theory for the global rise in obesity

JJ Heindel, RH Lustig, S Howard… - International Journal of …, 2024 - nature.com
Despite varied treatment, mitigation, and prevention efforts, the global prevalence and
severity of obesity continue to worsen. Here we propose a combined model of obesity, a …