Cyclic di-AMP, a multifaceted regulator of central metabolism and osmolyte homeostasis in Listeria monocytogenes

I Schwedt, M Wang, J Gibhardt, FM Commichau - Microlife, 2023 - academic.oup.com
Cyclic di-AMP is an emerging second messenger that is synthesized by many archaea and
bacteria, including the Gram-positive pathogenic bacterium Listeria monocytogenes. Listeria …

Differential stress responsiveness determines intraspecies virulence heterogeneity and host adaptation in Listeria monocytogenes

L Hafner, E Gadin, L Huang, A Frouin, F Laporte… - Nature …, 2024 - nature.com
Microbial pathogenesis is mediated by the expression of virulence genes. However, as
microbes with identical virulence gene content can differ in their pathogenic potential, other …

[HTML][HTML] ListiWiki: A database for the foodborne pathogen Listeria monocytogenes

C Elfmann, B Zhu, J Stülke, S Halbedel - International Journal of Medical …, 2023 - Elsevier
Listeria monocytogenes is a Gram positive foodborne pathogen that regularly causes
outbreaks of systemic infectious diseases. The bacterium maintains a facultative intracellular …

High density genomic surveillance and risk profiling of clinical Listeria monocytogenes subtypes in Germany

S Halbedel, S Wamp, R Lachmann, A Holzer… - Genome Medicine, 2024 - Springer
Background Foodborne infections such as listeriosis caused by the bacterium Listeria
monocytogenes represent a significant public health concern, particularly when outbreaks …

A comprehensive investigation of protein expression profiles in L. monocytogenes exposed to thermal abuse, mild acid, and salt stress conditions

F D'Onofrio, M Schirone, I Krasteva, M Tittarelli… - Frontiers in …, 2023 - frontiersin.org
Preventing L. monocytogenes infection is crucial for food safety, considering its widespread
presence in the environment and its association with contaminated RTE foods. The …

RECON gene disruption enhances host resistance to enable genome-wide evaluation of intracellular pathogen fitness during infection

CE Stamm, AP McFarland, MN Locke, H Tabakh… - Mbio, 2024 - journals.asm.org
Transposon sequencing (Tn-seq) is a powerful genome-wide technique to assess bacterial
fitness under varying growth conditions. However, screening via Tn-seq in vivo is …

Cytosolic Factors Controlling PASTA Kinase‐Dependent ReoM Phosphorylation

P Rothe, S Wamp, L Rosemeyer… - Molecular …, 2024 - Wiley Online Library
Bacteria adapt the biosynthesis of their envelopes to specific growth conditions and
prevailing stress factors. Peptidoglycan (PG) is the major component of the cell wall in Gram …

[HTML][HTML] Listeria monocytogenes uses de novo purine synthesis to enhance fitness in Lyoner-type sausage

PM Beindorf, JA Horlbog, IE Cuesta, C Guldimann… - Food Control, 2024 - Elsevier
Listeria monocytogenes is an important food-borne pathogen with high hospitalization and
case fatality rates. To cause disease, L. monocytogenes must gain access to a specific food …

Large multicountry outbreak of invasive Listeriosis by a listeria monocytogenes ST394 clone linked to smoked rainbow trout, 2020 to 2021

S Halbedel, I Sperle, R Lachmann, S Kleta… - Microbiology …, 2023 - Am Soc Microbiol
Whole-genome sequencing (WGS) has revolutionized surveillance of infectious diseases.
Disease outbreaks can now be detected with high precision, and correct attribution of …

[HTML][HTML] Proteins of the food-borne pathogen Listeria monocytogenes strain F2365 relevant to lethal acidic stress and during rapid inactivation

D Zhang, Z Liu, M Jia, JP Bowman - AIMS Agriculture and Food, 2024 - aimspress.com
Listeria monocytogenes, which causes human listeriosis after consumption of contaminated
food, can adapt and survive under a wide range of physiological and chemical stresses. In …